Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Contact sensitization in children with atopic dermatitis
Journal Information
Vol. 47. Issue 1.
Pages 47-51 (January - February 2019)
Download PDF
More article options
Vol. 47. Issue 1.
Pages 47-51 (January - February 2019)
Original Article
DOI: 10.1016/j.aller.2018.06.002
Contact sensitization in children with atopic dermatitis
D. Ozcekera,1,
Corresponding author

Corresponding author.
, F. Haslakb,1, F. Dilekc,1, S. Sipahid,1, E. Yucela,1, N. Gulerd,1, Z. Tamayd,1
a Saglik Bilimleri University, Okmeydani Education and Resarch Hospital, Department of Pediatric, Allergy and Immunolgy, Istanbul, Turkey
b Istanbul University, Istanbul Medical Faculty, Department of Pediatric, Istanbul, Turkey
c Bezmi Alem University, Medical Faculty, Department of Pediatric Allergy and Immunolgy, Istanbul, Turkey
d Istanbul University, Istanbul Medical Faculty, Department of Pediatric Allergy and Immunolgy, Istanbul, Turkey
Article information
Full Text
Download PDF
Tables (4)
Table 1. Demographic, clinical and laboratory features of the patients with atopic dermatitis.
Table 2. Cosmetic and european standard patch test results of the patients with atopic dermatitis.
Table 3. Association of some risk factors with sensitization to cosmetic and european standard patch test series.
Table 4. Evaluation of patch test results in atopic and non-atopic patients.
Show moreShow less

Atopic dermatitis is a common illness in childhood. Children with atopic dermatitis are prone to develop cutaneous sensitization due to skin barrier dysfunction.


The aim of this study was to evaluate the frequency of cutaneous sensitizations in patients with atopic dermatitis and to identify the most frequent causative allergens.

Study design

The study group consisted of 112 children with atopic dermatitis, aged 1–18 years (median 88.5 months) and 39 healthy controls, aged 1–8 years (median 88.48 months).


The diagnosis of atopic dermatitis was established by modified Hanifin and Rajka criteria; severity of the disease was assessed by scoring of atopic dermatitis. Serum blood eosinophil count, total IgE and skin prick tests for common aeroallergens and food allergens were performed. Patch tests with cosmetic series and European standard patch test series (Stallegenes© Ltd, Paris, France) were applied.


Of the children with atopic dermatitis, 17% (n=19) were sensitized to either cosmetic or standard series or both of them; no children in the control group had a positive patch test (p=0.001). Atopy and severity of atopic dermatitis was not a significant risk factor for cutaneous sensitization. The most common allergens were Nickel sulphate and Methychloroisothiazinolone (4.5% and 4.5%) in the European standard patch test and cocamidoproplybetaine (12.5%) in the cosmetic series patch test.


Cutaneous sensitization can develop in children with atopic dermatitis, therefore allergic contact dermatitis should be kept in mind.

Allergic contact
Patch tests


These are the options to access the full texts of the publication Allergologia et Immunopathologia

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe to

Allergologia et Immunopathologia

Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.