Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Awareness of allergic enterocolitis among primary-care paediatricians: A web-bas...
Journal Information
Vol. 44. Issue 5.
Pages 461-466 (September - October 2016)
Download PDF
More article options
Vol. 44. Issue 5.
Pages 461-466 (September - October 2016)
Original Article
DOI: 10.1016/j.aller.2016.03.002
Awareness of allergic enterocolitis among primary-care paediatricians: A web-based pilot survey
P. Comberiatia, M. Landib, A. Martellic, G.L. Piacentinia, C. Capristod, G. Paiolaa, D.G. Peronie,
Corresponding author

Corresponding author.
a Pediatric Clinic, Department of Life and Reproduction Sciences, University of Verona, Italy
b National System of Pediatric Primary Care, Asl To 1, Turin, Italy
c Pediatric Department, Santa Corona Hospital, Garbagnate Milanese, Milan, Italy
d Department of Pediatrics, Second University of Naples, Italy
e Department of Clinical and Experimental Medicine, Section of Paediatrics, University of Pisa, Italy
Article information
Full Text
Download PDF
Figures (3)
Show moreShow less
Tables (2)
Table 1. Clinical vignettes of suspected cases of FPIES. Multiple answers were allowed.
Table 2. Survey respondents’ opinion on diagnostic and therapeutic features of FPIES.
Show moreShow less

Allergic enterocolitis, also known as food protein-induced enterocolitis syndrome (FPIES), is an increasingly reported and potentially severe non-IgE mediated food allergy of the first years of life, which is often misdiagnosed due to its non-specific presenting symptoms and lack of diagnostic guidelines.


We sought to determine the knowledge of clinical, diagnostic and therapeutic features of FPIES among Italian primary-care paediatricians.


A 16-question anonymous web-based survey was sent via email to randomly selected primary care paediatricians working in the north of Italy.


There were 194 completed surveys (48.5% response rate). Among respondents, 12.4% declared full understanding of FPIES, 49% limited knowledge, 31.4% had simply heard about FPIES and 7.2% had never heard about it. When presented with clinical anecdotes, 54.1% recognised acute FPIES and 12.9% recognised all chronic FPIES, whereas 10.3% misdiagnosed FPIES as allergic proctocolitis or infantile colic. To diagnose FPIES 55.7% declared to need negative skin prick test or specific-IgE to the trigger food, whereas 56.7% considered necessary a confirmatory oral challenge. Epinephrine was considered the mainstay in treating acute FPIES by 25.8% of respondents. Only 59.8% referred out to an allergist for the long-term reintroduction of the culprit food. Overall, 20.1% reported to care children with FPIES in their practice, with cow's milk formula and fish being the most common triggers; the diagnosis was self-made by the participant in 38.5% of these cases and by an allergist in 48.7%.


There is a need for promoting awareness of FPIES to minimise delay in diagnosis and unnecessary diagnostic and therapeutic interventions.

Food allergy
Food protein-induced enterocolitis syndrome


These are the options to access the full texts of the publication Allergologia et Immunopathologia

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe to

Allergologia et Immunopathologia

Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 19,34 €

Comprar ahora
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.