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Vol. 47. Issue 3.
Pages 289-294 (May - June 2019)
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Vol. 47. Issue 3.
Pages 289-294 (May - June 2019)
DOI: 10.1016/j.aller.2018.03.010
Asthma, exercise and metabolic dysregulation in paediatrics
Manlio Milanesea, Emanuele Miraglia del Giudiceb, Diego G. Peronic,
Corresponding author

Corresponding author.
a Division of Respiratory Diseases, Azienda Sanitaria Locale 2 Savonese, Savona, Italy
b Department of Women, Child and General and Special Surgery, Università della Campania Luigi Vanvitelli, Naples, Italy
c Department of Clinical and Experimental Medicine, Section of Paediatric, University of Pisa, Pisa, Italy
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Table 1. [{Table I)}] The “do not” strategy in asthma, exercise and obesity.

Asthma is the most frequent chronic disease in childhood. Chest tightness, cough, wheezing and dyspnoea during or after exercise may be unique manifestations of asthma in up to 90% of subjects. Physical activity may be reduced by uncontrolled asthma symptoms and parental beliefs, impairing physical fitness of asthmatic children. Clinicians working in the field of allergy are aware of evidence supporting the benefits of physical activity for patients with asthma. Treatment of asthma is required in order to obtain its control and to avoid any limitation in sports and active play participation. As exercise performance in children with controlled asthma is not different from that of healthy controls, any exercise limitation cannot be accepted. Overweight and obesity may interfere with asthma and exercise, leading to dyspnoea symptoms. Evidences on the effect of insulin resistance on airway smooth muscle and on bronchial hyperactivity are presented.


Exercise is part of the strategy to obtain the best control of asthma in childhood, but we have to optimise the asthma control therapy before starting exercise programming. Furthermore, it is crucial to give best attention on the effects of obesity and insulin resistance, because they could in turn influence patients’ symptoms.

Smooth muscle


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