Share
array:23 [ "pii" => "S0210480608738592" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73859-2" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73859" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:435-42" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1248 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 796 "PDF" => 446 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480608738609" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73860-9" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73860" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:443-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1790 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 1189 "PDF" => 592 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Comparación de la concentración espermática usando la cámara de Makler y la cámara de Neubauer" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "443" "paginaFinal" => "445" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Comparing the sperm concentration determined by the makler and the neubauer chambers" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "W. Cardona-Maya, J. Berdugo, A. Cadavid" "autores" => array:3 [ 0 => array:2 [ "nombre" => "W." "apellidos" => "Cardona-Maya" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Berdugo" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Cadavid" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608738609?idApp=UINPBA00004N" "url" => "/02104806/0000003200000004/v1_201304251904/S0210480608738609/v1_201304251904/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480608738580" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73858-0" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73858" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:430-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1196 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 737 "PDF" => 453 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Trasplante cardio-renal. Evolucion del injerto renal" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "430" "paginaFinal" => "434" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Renal graft outcome in patients with combined heart-kidney transplantation" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.L. Gutiérrez baños, J.A. Portillo martín, C. Conde redondo, Aguilera Tubet carmen, R. Ballesterodiego, S. Zubillaga guerrero, E. Ramos barselo" "autores" => array:7 [ 0 => array:2 [ "nombre" => "J.L." "apellidos" => "Gutiérrez baños" ] 1 => array:2 [ "nombre" => "J.A." "apellidos" => "Portillo martín" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Conde redondo" ] 3 => array:2 [ "nombre" => "Aguilera" "apellidos" => "Tubet carmen" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Ballesterodiego" ] 5 => array:2 [ "nombre" => "S." "apellidos" => "Zubillaga guerrero" ] 6 => array:2 [ "nombre" => "E." "apellidos" => "Ramos barselo" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608738580?idApp=UINPBA00004N" "url" => "/02104806/0000003200000004/v1_201304251904/S0210480608738580/v1_201304251904/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Respuesta inmunohumoral durante la nefrectomía abierta y laparoscópica de donante vivo. Modelo porcino experimental" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "435" "paginaFinal" => "442" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Sáenz Medina, M.S. Asuero de Lis, J. Villafruela Sanz, C. Correa Gorospe, B. Cuevas, J. Galindo álvarez, A. Páez Borda, A.I. Linares Quevedo, R. Marcén Letosa, J. Pascual Santos, F.J. Burgos Revilla" "autores" => array:11 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "Sáenz Medina" "email" => array:1 [ 0 => "javiersaenzmedina@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0030" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M.S." "apellidos" => "Asuero de Lis" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "J." "apellidos" => "Villafruela Sanz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "C." "apellidos" => "Correa Gorospe" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "B." "apellidos" => "Cuevas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 5 => array:3 [ "nombre" => "J." "apellidos" => "Galindo álvarez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">****</span>" "identificador" => "aff0020" ] ] ] 6 => array:3 [ "nombre" => "A." "apellidos" => "Páez Borda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0030" ] ] ] 7 => array:3 [ "nombre" => "A.I." "apellidos" => "Linares Quevedo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0030" ] ] ] 8 => array:3 [ "nombre" => "R." "apellidos" => "Marcén Letosa" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 9 => array:3 [ "nombre" => "J." "apellidos" => "Pascual Santos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 10 => array:3 [ "nombre" => "F.J." "apellidos" => "Burgos Revilla" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*****</span>" "identificador" => "aff0025" ] ] ] ] "afiliaciones" => array:6 [ 0 => array:3 [ "entidad" => "Servicio de Urología Hospital de Fuenlabrada" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0030" ] 1 => array:3 [ "entidad" => "Servicio de Anestesiología y Reanimación" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 2 => array:3 [ "entidad" => "Servicio de Nefrología" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] 3 => array:3 [ "entidad" => "Unidad de Investigación" "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] 4 => array:3 [ "entidad" => "Servicio de Cirugía" "etiqueta" => "****" "identificador" => "aff0020" ] 5 => array:3 [ "entidad" => "Servicio de Urología. Hospital Ramón y Cajal. Universidad de Alcalá de Henares" "etiqueta" => "*****" "identificador" => "aff0025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. J. Sáenz Medina Servicio de Urología. Hospital de Fuenlabrada Camino del Molino, s/n – 28942 Fuenlabrada (Madrid) Tel.: 916 006 000" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Immune response during laparoscopic and open living donor nephrectomy. An experimental pig model" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-09-01" "fechaAceptado" => "2007-10-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88576" "palabras" => array:3 [ 0 => "Laparoscopia" 1 => "Nefrectomía" 2 => "Respuesta inmunohumoral" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88575" "palabras" => array:3 [ 0 => "Laparoscopy" 1 => "Nephrectomy" 2 => "Immune response" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Respuesta inmunohumoral durante la nefrectomía abierta y laparoscópica de donante vivo. Modelo porcino experimental</p> <span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se ha demostrado la menor agresividad quirúrgica provocada por el abordaje laparoscópico, en base a la medición de diversos marcadores de estrés postquirúrgico, entre los que se encuentran distintas interleuquinas (IL) y la proteína C reactiva (PCR). La endotelina 1 (ET-1) es un vasoconstrictor potente producido en el endotelio renal escasamente analizado en el curso de la cirugía laparoscópica. El objetivo del trabajo es analizar comparativamente la respuesta inmunohumoral inducida por las nefrectomías laparoscópica y abierta en un modelo experimental porcino, en base a la cuantificación de la PCR, las IL-2, 10, el factor de necrosis tumoral alfa (TNF alfa), y la ET-1</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se analizan comparativamente dos grupos de cerdos de 25-40 Kg, un grupo CONTROL (N=10) y grupo LAPAROSCÓPICO (N=10), a los que se les realiza una nefrectomía abierta o laparoscópica respectivamente. Se determinó en sangre venosa periférica los niveles de PCR, IL-2, IL-10, TNF α y ET-1. Las determinaciones analíticas se realizaron en los momentos: basal, postcirugía, 1, 3, 5, y 7 días postquirúrgico</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El análisis comparativo de ambos grupos demuestra un aumento estadísticamente significativo de la PCR (1,44+ 0,88 vs 1,32 + 0,14 mg/dl, p=0,046), TNF α (131,14 + 41,37 vs 57,19 + 23,71 pg/ml, p>0,001) y ET-1 (0,91 + 0,49 vs 0,56 + 0,5 fmol/ml, p=0,001) del grupo abierto en comparación con el grupo control, así como una elevación de la IL- 2 en el grupo laparoscópico</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La respuesta inmunohumoral inducida por la nefrectomía abierta es superior a la de la nefrectomía laparoscópica en el curso de la donación. La importancia de este hecho en el síndrome isquemia reperfusión o la functión inmediata del injerto no está claramente establecida</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Immune response during laparoscopic and open living donor nephrectomy. An experimental pig model</p> <span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">It’s been demonstrated laparoscopic access determines a lower surgical stress, by measurement of several markers as different interleuquines (IL) or C- reactive protein (CRP). Endothelin 1 (ET-1) is a powerful vasoconstrictor produced in renal endothelium scarcely studied in laparoscopy. The objective of this study is to analyze immune response during laparoscopic and open donor nephrectomy, in a porcine experimental model by means of measuring IL-2, 10, tumoral necrosis factor α (TNFα), CRP and ET-1</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Twenty pigs underwent left nephrectomy, 10 by laparoscopy and 10 by open approach in an experimental model. Both groups were monitorized IL-2, 10, TNF α, ET-1 at basal, immediately post surgery, first, third, fifth and seventh days after procedure</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The comparative analysis between groups demonstrated a significant increase in levels of CRP (1,44 + 0,88 vs 1,32 + 0,14 mg/dl, p=0,046), TNF α (131,14 + 41,37 vs 57,19 + 23,71 pg/ml, p>0,001) and ET-1 (0,91 + 0,49 vs 0,56 + 0,5 fmol/ml, p=0,001) of open nephrectomy group, as a higher levels of IL-2 in laparoscopic group</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Open donor nephrectomy determines a higher immune response than laparoscopic approach. The importance of this fact over the ischemia-reperfusion syndrome or the immediate function of graft is not clearly established</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:31 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The serum interleukin 6 response to elective surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Shenkin" 1 => "W.D. Fraser" 2 => "J. Series" 3 => "F.P. Winstanley" 4 => "A.C. McCartney" 5 => "H.J. Burns" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lymphokine Cytokine Res" "fecha" => "1989" "volumen" => "8" "numero" => "2" "paginaInicial" => "123" "paginaFinal" => "127" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interleukin-6 as a new indicator of inflammatory status: detection of serum levels of interleukin-6 and C-reactive protein after surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:7 [ 0 => "H. Ohzato" 1 => "K. Yoshizaki" 2 => "N. Nishimoto" 3 => "A. Ogata" 4 => "H. Tagoh" 5 => "M. Monden" 6 => "M. Gotoh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Surgery" "fecha" => "1992" "volumen" => "111" "numero" => "2" "paginaInicial" => "201" "paginaFinal" => "209" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1736391" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in T cell subsets, interleukin-6 and C-reactive protein after laparoscopic and open colorectal resection for malignancy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B.J. Mehigan" 1 => "J.E. Hartley" 2 => "P.J. Drew" 3 => "A. Saleh" 4 => "P.C. Dore" 5 => "P.W. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s004640020021" "Revista" => array:7 [ "tituloSerie" => "Surg Endosc" "fecha" => "2001" "volumen" => "15" "numero" => "11" "paginaInicial" => "1289" "paginaFinal" => "1293" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11727135" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Elevation of circulating interleukin 6 after surgery: factors influencing the serum level" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K. Sakamoto" 1 => "H. Arakawa" 2 => "S. Mita" 3 => "T. Ishiko" 4 => "S. Ikei" 5 => "H. Egami" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Cytokine" "fecha" => "1994" "volumen" => "6" "numero" => "2" "paginaInicial" => "181" "paginaFinal" => "186" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8032001" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic cytokine response after major surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.J. Baigrie" 1 => "P.M. Lamont" 2 => "D. Kwiatkowski" 3 => "M.J. Dallman" 4 => "P.J. Morris" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Surg" "fecha" => "1992" "volumen" => "79" "numero" => "8" "paginaInicial" => "757" "paginaFinal" => "760" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1393463" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic-assisted vs. open surgery for colorectal cancer: comparative study of immune effects" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P.M. Hewitt" 1 => "S.M. Ip" 2 => "S.P. Kwok" 3 => "S.S. Somers" 4 => "K. Li" 5 => "K.L. Leung" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Dis Colon Rectum" "fecha" => "1998" "volumen" => "41" "numero" => "7" "paginaInicial" => "901" "paginaFinal" => "909" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9678378" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0212656708000218" "estado" => "S300" "issn" => "02126567" ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prospective randomized study of laparoscopic versus open colonic resection for adenocarcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.G. Stage" 1 => "S. Schulze" 2 => "P. Moller" 3 => "H. Overgaard" 4 => "M. Andersen" 5 => "V.B. Rebsdorf-Pedersen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Surg" "fecha" => "1997" "volumen" => "84" "numero" => "3" "paginaInicial" => "391" "paginaFinal" => "396" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9117320" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic inflammatory responses during laparoscopic and open inguinal hernia repair: a randomised prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Jess" 1 => "K. Schultz" 2 => "K. Bendtzen" 3 => "O.H. Nielsen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/110241500750008600" "Revista" => array:7 [ "tituloSerie" => "Eur J Surg" "fecha" => "2000" "volumen" => "166" "numero" => "7" "paginaInicial" => "540" "paginaFinal" => "544" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10965832" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic cytokine response after laparoscopic-assisted resection of rectosigmoid carcinoma: a prospective randomized trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.L. Leung" 1 => "P.B. Lai" 2 => "R.L. Ho" 3 => "W.C. Meng" 4 => "R.Y. Yiu" 5 => "J.F. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Ann Surg" "fecha" => "2000" "volumen" => "231" "numero" => "4" "paginaInicial" => "506" "paginaFinal" => "511" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10749610" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perioperative plasma concentrations of tumor necrosis factoralpha and interleukin-6 in infected patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G.J. Tang" 1 => "C.D. Kuo" 2 => "T.C. Yen" 3 => "H.S. Kuo" 4 => "K.H. Chan" 5 => "H.W. Yien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Crit Care Med" "fecha" => "1996" "volumen" => "24" "numero" => "3" "paginaInicial" => "423" "paginaFinal" => "428" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8625629" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S001425651170008X" "estado" => "S300" "issn" => "00142565" ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cellular and humoral inflammatory response after laparoscopic and conventional colorectal resections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Ordemann" 1 => "C.A. Jacobi" 2 => "W. Schwenk" 3 => "R. Stösslein" 4 => "J.M. Müller" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s004640090032" "Revista" => array:7 [ "tituloSerie" => "Surg Endosc" "fecha" => "2001" "volumen" => "15" "numero" => "6" "paginaInicial" => "600" "paginaFinal" => "608" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11591950" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interleukin-10. A role in the development of postoperative immunosuppression" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Klava" 1 => "A.C. Windsor" 2 => "S.M. Farmery" 3 => "L.F. Woodhouse" 4 => "J.V. Reynolds" 5 => "C.W. Ramsden" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Surg" "fecha" => "1997" "volumen" => "132" "numero" => "4" "paginaInicial" => "425" "paginaFinal" => "429" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9108765" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory response after laparoscopic and conventional colorectal resections results of a prospective randomized trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W. Schwenk" 1 => "C. Jacobi" 2 => "U. Mansmann" 3 => "B. Böhm" 4 => "J.M. Müller" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Langenbecks Arch Chir" "fecha" => "2000" "volumen" => "385" "numero" => "1" "paginaInicial" => "2" "paginaFinal" => "9" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Response of serum interleukin-6 in patients undergoing elective surgery of varying severity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.M. Cruickshank" 1 => "W.D. Fraser" 2 => "H.J. Burns" 3 => "J. Van Damme" 4 => "A. Shenkin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Clin Sci" "fecha" => "2005" "volumen" => "79" "numero" => "2" "paginaInicial" => "161" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2167805" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interleukin-6 as a new indicator of inflammatory status: detection of serum levels of interleukin-6 and Creactive protein after surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H. Ohzato" 1 => "K. Yoshizaki" 2 => "N. Nishimoto" 3 => "A. Ogata" 4 => "H. Tagoh" 5 => "M. Monden" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Surgery" "fecha" => "2005" "volumen" => "111" "numero" => "2" "paginaInicial" => "201" "paginaFinal" => "209" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1736391" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Update on the mechanism of immune suppression of injury and immune modulation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Faist" 1 => "C. Schinkel" 2 => "S. Zimmer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "World J Surg" "fecha" => "1996" "volumen" => "20" "numero" => "4" "paginaInicial" => "454" "paginaFinal" => "459" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8662134" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endothelins" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E.R. Levin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199508103330607" "Revista" => array:7 [ "tituloSerie" => "N Engl J Med" "fecha" => "1995" "volumen" => "333" "numero" => "6" "paginaInicial" => "356" "paginaFinal" => "363" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7609754" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intra-abdominal pressure during pneumoperitoneum stimulates endothelin release in a canine model" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "B.D. Hamilton" 1 => "G.K. Chow" 2 => "N.T. Stowe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.1998.12.193" "Revista" => array:8 [ "tituloSerie" => "J Endourol" "fecha" => "1998" "volumen" => "12" "numero" => "2" "paginaInicial" => "193" "paginaFinal" => "197" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9607449" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0014256510001050" "estado" => "S300" "issn" => "00142565" ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pneumoperitoneum upregulates preproendothelin-1 messenger RNA" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.A. Ambrose" 1 => "R.P. Onders" 2 => "N.T. Stowe" 3 => "M.S. Simonson" 4 => "A.V. Robinson" 5 => "S. Wilhelm" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Surg Endosc" "fecha" => "2001" "volumen" => "15" "numero" => "2" "paginaInicial" => "183" "paginaFinal" => "188" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11285964" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Why is urologycal laparoscopy minimally invasive?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P. Fornara" 1 => "C. Doehn" 2 => "M. Seyfarth" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "52351" "Revista" => array:7 [ "tituloSerie" => "Eur Urol" "fecha" => "2000" "volumen" => "37" "numero" => "3" "paginaInicial" => "241" "paginaFinal" => "250" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10720847" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory response after abdominal surgery. Best Pract Res" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B. Sido" 1 => "J.R. Teklote" 2 => "M. Hartel" 3 => "H. Friess" 4 => "M.W. Büchler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Clin Anaesthesiol" "fecha" => "2004" "volumen" => "18" "numero" => "3" "paginaInicial" => "439" "paginaFinal" => "454" "itemHostRev" => array:3 [ "pii" => "S0140673611609884" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of Pneumoperitoneum on Hemodynamic and Systemic Immunologic Responses to Peritonitis in Pigs" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E.M. Clary" 1 => "S.M. Bruch" 2 => "C.L. Lau" 3 => "A. Ali" 4 => "E.G. Chekan" 5 => "M.J. Garcia-Oria" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Surg Res" "fecha" => "2002" "volumen" => "108" "numero" => "1" "paginaInicial" => "32" "paginaFinal" => "38" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12443712" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The acute phase response" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "H. Baumann" 1 => "J. Gauldie" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0167-5699(94)90137-6" "Revista" => array:7 [ "tituloSerie" => "Immunol Today" "fecha" => "1994" "volumen" => "15" "numero" => "2" "paginaInicial" => "74" "paginaFinal" => "80" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7512342" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mediators of injury and inflammation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Schlag" 1 => "H. Redl" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "World J Surg" "fecha" => "1996" "volumen" => "20" "numero" => "4" "paginaInicial" => "406" "paginaFinal" => "410" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8662127" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prospective comparison of the imunological and stress response folowing laparoscopic and open surgery for localized renal cell carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J. Landman" 1 => "E. Olweny" 2 => "C.P. Sundaram" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.ju.0000118649.56016.1c" "Revista" => array:6 [ "tituloSerie" => "J Urol" "fecha" => "2004" "volumen" => "171" "paginaInicial" => "1456" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15017197" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0212656711000461" "estado" => "S300" "issn" => "02126567" ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparative evaluation of immune response after laparoscopical and open total mesorectal excisions with anal sphincter preservation in patients with rectal cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J. Hu" 1 => "Z. Zhou" 2 => "Z. Chen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "World J Gastroenterol" "fecha" => "2003" "volumen" => "9" "paginaInicial" => "2690" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14669314" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio comparativo de la función del transplante renal con donante vivo mediante nefrectomía convencional y laparoscópica. Influencia del síndrome de isquemia repercusión" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.I. Linares Quevedo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:1 [ "serieFecha" => "2005" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endocrine and Inmune response to injury after open and laparoscopic cholecystectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J.M. Bellon" 1 => "L. Manzano" 2 => "A. Larrad" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int Surg" "fecha" => "1998" "volumen" => "83" "paginaInicial" => "24" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9706511" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The acute-phase response" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:2 [ 0 => "H.J. Pannen" 1 => "J.L. Robotham" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "New Horiz" "fecha" => "1995" "volumen" => "3" "paginaInicial" => "183" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7583160" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic and Cell-Mediated Immune Response after Laparoscopic and Open Cholecystectomy in paitients with chronic liver disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.B. Lausten" 1 => "T.M. Ibrahim" 2 => "T. El-Sefi" 3 => "L.S. Jensen" 4 => "B. Gesser" 5 => "C.G. Larsen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Dig Surg" "fecha" => "1999" "volumen" => "16" "numero" => "6" "paginaInicial" => "471" "paginaFinal" => "477" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10805546" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokine response to surgical stress: comparison of pure laparoscopic, hand-assisted laparoscopic, and open nephrectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E.D. Matsumoto" 1 => "V. Margulis" 2 => "L. Tunc" 3 => "G.D. Taylor" 4 => "D. Duchene" 5 => "D.B. Johnson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.2005.19.1140" "Revista" => array:7 [ "tituloSerie" => "J endourol" "fecha" => "2005" "volumen" => "19" "numero" => "9" "paginaInicial" => "1140" "paginaFinal" => "1145" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16283854" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/02104806/0000003200000004/v1_201304251904/S0210480608738592/v1_201304251904/es/main.assets" "Apartado" => array:4 [ "identificador" => "6429" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Original" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/02104806/0000003200000004/v1_201304251904/S0210480608738592/v1_201304251904/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608738592?idApp=UINPBA00004N" ]
