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Vol. 39. Issue 6.
Pages 349-353 (July - August 2015)
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Vol. 39. Issue 6.
Pages 349-353 (July - August 2015)
Original article
Municipal distribution and trends in bladder cancer incidence in health area of León, Spain (1996–2010)
Tendencia y distribución municipal de la incidencia de cáncer de vejiga en el área de salud de León (1996–2010)
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M. del Cantoa, L. García-Martínezb,
Corresponding author
lgarm@unileon.es

Corresponding author.
, T. Fernández-Villab, A.J. Molinab, F. Campanarioa, M. García-Sanza, G. López-Abentec,d, E. Honradoe, V. Martín-Sánchezb,d
a Servicio de Urología, Complejo Asistencial Universitario de León, León, Spain
b Grupo de Investigación en Interacción Gen-Ambiente-Salud, Universidad de León, León, Spain
c Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain
d Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
e Servicio de Anatomía Patológica, Complejo Asistencial Universitario de León, León, Spain
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Table 1. Distribution of cases, population, and rates of bladder cancer in the health area of León (1996–2010).
Abstract
Objective

Spain is a country where bladder cancer incidence and mortality rates are some of the highest in the world. The aim of this study is to know the incidence, trends and geographical distribution of bladder cancer in the health area of León.

Material and methods

The new cases of bladder cancer (CIE-188) in patients residing in the health area of León and registered in the Hospital Tumor Registry of the Centro Asistencial Universitario in León (Spain) between 1996 and 2010 were included in this study. Triennial crude incidence and adjusted incidence rates to the worldwide and European population were calculated. Population data of the municipalities of Leon (Spain) were obtained from National Institute of Statistic of Spain (INE, Instituto Nacional de Estadística). Data were disaggregated by sex-groups and five-year age groups. Spatial distribution of smoothed municipal relative risks (RR) of bladder cancer was carried out using a Besag, York and Mollié model. Bayesian model were used to calculate the posterior probability (PP) of RR>1.

Results

1573 cases were included. Incidence rates standardized to European population increased among men from 20.8/100,000 (1996–98) to 33.1/100,000 (2006–2008) and among women these rates increased from 1.9/100,000 to 5.9/100,000 for the same period of time. No relevant differences were found in the municipal distribution of the incidences.

Conclusions

Bladder cancer incidence rates are high in the European context. Rising trends in incidence in both sexes, particularly in women are observed.

Keywords:
Bladder cancer
Incidence
Tendency
Epidemiology
Resumen
Objetivo

España presenta unas de las tasas más elevadas de incidencia y mortalidad por cáncer de vejiga del mundo. El presente estudio tiene por objeto conocer la incidencia, tendencia y distribución geográfica del cáncer de vejiga en el área de salud de León.

Material y métodos

Fueron incluidos los casos nuevos de cáncer de vejiga (CIE-188) del registro hospitalario de tumores del Centro Asistencial Universitario de León, entre 1996–2010 con residencia en el ASL. Se calcularon las incidencias brutas trienales y ajustadas a población mundial y europea. Como denominador se utilizaron los datos del INE de población desagregada por sexo y grupos quinquenales de edad de residentes en municipios del ASL. Para el análisis de la distribución espacial se estimaron los riesgos relativos (RR) municipales suavizados mediante el ajuste del modelo de Besag, York y Mollié y sus probabilidades posteriores de que los RR fuesen>1 (PP), utilizando métodos bayesianos.

Resultados

Se incluyeron 1.573 casos. Las tasas estandarizadas a población europea ascendieron de 20,8 (1996–98) a 33,1 (2006–2008) casos nuevos por 100.000 hombres y de 1,9 a 5,9 en las mujeres. No se observaron diferencias de interés en la distribución municipal de las incidencias.

Conclusiones

Las tasas de incidencia observadas son elevadas en el contexto europeo. Se observan tendencias ascendentes en hombres y especialmente relevantes en mujeres.

Palabras clave:
Cáncer de vejiga
Incidencia
Tendencia
Epidemiología

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