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Vol. 54. Issue 6.
Pages 470-473 (July 2003)
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Vol. 54. Issue 6.
Pages 470-473 (July 2003)
Tumor pardo óseo como primera manifestación de hiperparatiroidismo primario
Brown bone tumour as the first manifestation of primary hyperparathyroidism
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M. Marcos garcía1,*, V. Pino rivero**, T. Keituqwa yáñez**, M. Alcaraz fuentes*, G. Trinidad ruiz*, A. Blasco huelva***
* Médico residente de orl
** F.E.A. ORL
*** Jefe de servicio de orl. hospital infanta cristina. badajoz
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Resumen

Presentamos el caso clínico de una mujer de 26 años que refería tumoración mentoniana de 2 años de evolución con hipercalcemia (11,8 mg/dl) y PTH (paratohormona) de 761 pg/ml. Se realizó TAC mandibular y RMN, así como biopsia del tumor con exéresis del mismo por parte del Servicio de Máxilo-Facial. Nuestro Servicio de O.R.L. solicitó una gammagrafía (Tc99 S-mibi) y TAC cérvicotorácico que informaban de la presencia de una lesión que, tras cirugía y estudio AP, resultó ser un adenoma de paratiroides inferior derecha. El hiperparatiroidismo primario que presentaba la paciente era el estímulo principal del tumor pardo, formado por células gigantes multinucleadas y macrófagos, siendo éste la primera manifestación del desorden metabólico. Esta presentación del hiperparatiroidismo es muy poco frecuente en la clínica. Realizamos una revisión de la literatura y establecemos el diagnóstico diferencial para tal patología.

Palabras clave:
Tumor Pardo
Hiperparatiroidismo Primario
Abstract

We report a clinical case of a 26 years old female who had a 2 years evolution chin tumour with hypercalcemia (11,8 mg/dl) and PTH (paratohormone) of 761 pg/ml. She underwent a CT scan and MRI of the mandible, as well as a biopsy followed by excision of the tumour by the maxilofacial surgeons. Our ENT Department asked for a Scintigraphy (Tc99s-mibi) and thoraciccervical CT, which showed a lesion that turned out to be an adenoma of the lower right parathyroid gland after sugery and pathological examination. The patient suffered a Primary hyperparathyroidism that was the main stimulus for the Brown Tumour made up by macrophagos and multinuclear giant cells, being this the first manifestation of the metabolic disorder. This form of hyperparathyroidism is very rare in the clinic. We do a literature review to establish the differential diagnosis for such pathology.

Key words:
Brown Tumour
Primary Hyperparathyroidism

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