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Vol. 56. Issue 2.
Pages 63-67 (February 2005)
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Vol. 56. Issue 2.
Pages 63-67 (February 2005)
Estudio estadístico y resultados clínicos de la comparación de dos protocolos diferentes en el tratamiento de la hipoacusia brusca
Statistical study and clinical results by comparison of two different protocols in the treatment of sudden hearing loss
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V. Pino Rivero
,a
Corresponding author
vicentepinorivero@terra.com

Vicente Pino Rivero Avda. Antonio Masa, 3, 5º-G 06005 Badajoz
, G. Trinidad Ruíz**, M. Marcos García**, C. Montero García*, A. González Palomino**, C.G. Pantoja Hernández**, G. Pardo Romero**, A. Blasco Huelva***
* Facultativo Especialista de Otorrinolaringología
** Médico Residente de ORL
*** Jefe de Servicio de ORL. Complejo Hospitalario Infanta Cristina. Badajoz
Article information
Resumen

La sordera súbita continúa siendo una entidad clínica de etiología desconocida para la cual se han propuesto diversas teorías y tratamientos. Presentamos un estudio comparativo de dos protocolos diferentes que hemos utilizado en 60 pacientes (divididos en dos grupos de 30) diagnosticados e ingresados por hipoacusia brusca entre los años 1989 y 2003. El objetivo principal es comprobar si existe diferencia estadísticamente significativa entre ambos, respecto a la mejoría auditiva obtenida, tras al menos dos semanas de tratamiento. Aplicamos la aproximación normal de la prueba de Mann-Whitney y defendemos, tras su resultado, nuestro protocolo actual (piracetam, pentoxifilina, metilprednisolona), que comprende 4 días de tratamiento intravenoso y 10 más de tratamiento domiciliario. La presencia de síntomas vestibulares asociados ensombrece el pronóstico pues casi el 95% de los pacientes que los presentaban no experimentaron recuperación significativa (p<0,05)

Palabras clave:
Sordera súbita
Hipoacusia brusca
Protocolo
Mann-Whitney
Abstract

Sudden deafness goes on being a clinical entity of unknown cause for which several theories and treatments have been proposed. We are reporting a comparative study of two different protocols that we have performed on 60 patients (divided in two groups of 30) diagnosed and admitted with sudden hearing loss between 1989 and 2003. The main goal is to prove if there is a statistical and significant difference among both, in respect of the audiologic improvement obtained, after two weeks of therapy at east. We have applied the normal approximation of Mann-Whitney´s test and we can argue, after its result, our current protocol (piracetam, pentoxifiline, metilprednisolone), which includes 4 days of endovenous treatment another 10 days at home. The presence of vestibular symptoms darkens the prognosis since about 95% of the patients with them have not improved significantly (p<0.05)

Key words:
Sudden deafness
Sudden hearing loss
Protocol
Mann-Whitney

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