Buscar en
Acta Otorrinolaringológica Española
Toda la web
Inicio Acta Otorrinolaringológica Española Carcinoma epidermoide de laringe estadio IV. Evolución a largo plazo
Journal Information
Vol. 57. Issue 9.
Pages 419-424 (November 2006)
Share
Share
Download PDF
More article options
Vol. 57. Issue 9.
Pages 419-424 (November 2006)
Carcinoma epidermoide de laringe estadio IV. Evolución a largo plazo
Epidermoid carcinoma larynx in stage IV
Visits
2080
J. Herranz González-Botas1
Corresponding author
jhg@canalejo.org

Correspondencia: Jesús Herranz González-Botas Rua Courel, 6 15179 Oleiros (A Coruña)
, J.C. Vázquez Barro
Servicio de Otorrinolaringología. Hospital Universitario Juan Canalejo. A Coruña
This item has received
Article information
Resumen
Objetivo

Analizar supervivencia, recidiva local, regional, a distancia y segundos primarios en estadios IV de laringe tratados con cirugía y radioterapia.

Material

Estudio retrospectivo de 147 pacientes tratados con cirugía ± radioterapia, con un seguimiento mínimo de 5 años.

Resultados

Supervivencia global y causa específica a 5 y 10 años de 42%, 35% y 49%, 45,8% respectivamente. Control locoregional del 57,7 % y 54,7% a los 5 y 10 años. Recidivas locales 25,7%, recidivas regionales 74,2%, y metástasis a distancia 10,9%. Segundos primarios 12%, el 50% en pulmón. Se analizan factores que pueden influir en la supervivencia.

Conclusiones

En nuestra experiencia, la cirugía, con radioterapia complementaria en N+, permite curar un 45% de los estadios IV de laringe. La recidiva regional es la causa más frecuente de fracaso, influida por el N+, apareciendo en los primeros 36 meses de evolución.

Palabras clave:
Cáncer de laringe
Cirugía
Recidiva
Metástasis
Segundo primario
Abstract
Objective

To determine the survival, loco-regional control, distant metastases and second primary in stage IV laryngeal carcinoma treated by surgery and radiotherapy.

Material

Retrospective study of 147 patients treated with surgery and radiotherapy with a 5 year minimun follow-up.

Results

Overall and cause specific survival at 5 and 10 years was 42%, 35% and 49%, 45.8% respectively. Loco-regional control was 57.7 % and 54.7% at 5 and 10 years. Local recurrences presented in 25.7%, regional recurrences in 74.2%, and distant metastases 10.9%. Second primary tumors developed in 12% of the patients, 50% of the cases in the lungs. Factors related to survival are evaluated.

Conclusions

In our experience, surgery with postoperative radiotherapy in N+, controls 45% of stage IV laryngeal carcinoma. Regional recurrencies are the main cause of failure, more frequent in N+ patientes, present in the first 36 months after treatment.

Key words:
Larynx carcinoma
Surgery
Recurrence
Distant metastasis
Second primary

Article

These are the options to access the full texts of the publication Acta Otorrinolaringológica Española
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Acta Otorrinolaringológica Española

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos