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Inicio Acta Otorrinolaringológica Española Comparative study on Saliva and Nasopharyngeal swabs and the outcome of RT-PCR t...
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Vol. 74. Issue 5.
Pages 315-319 (September - October 2023)
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Vol. 74. Issue 5.
Pages 315-319 (September - October 2023)
Original article
Comparative study on Saliva and Nasopharyngeal swabs and the outcome of RT-PCR test in patients with mild symptoms of SARS-CoV-2
Estudio comparativo de muestras de saliva y nasofaríngeas y el resultado de la prueba RT-PCR en pacientes con síntomas leves de SARS-CoV-2
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Satvinder Singh Bakshia,
Corresponding author
saty.bakshi@gmail.com

Corresponding author.
, V. Mangayarkarasib, Debabrata Dashb, Soumyajit Dasa, Seepana Ramesha, Cheeranjeevi Jayamc, Vinoth Kumar Kalidossd
a Department of ENT and Head & Neck Surgery, All India Institute of Medical Sciences Mangalagiri, Guntur, Andhra Pradesh, India
b Department of Microbiology, AIIMS Mangalagiri, Guntur, Andhra Pradesh, India
c Department of Dentistry, AIIMS Mangalagiri, Guntur, Andhra Pradesh, India
d Department of Community and Family Medicine, AIIMS Mangalagiri, Guntur, Andhra Pradesh, India
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Statistics
Tables (3)
Table 1. Age wise distribution of the samples (n = 405).
Table 2. Comparison of nasopharyngeal swab and saliva (2 × 2 Chi-square table).
Table 3. Ct value comparisons of various genes in nasopharyngeal swab & saliva.
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Abstract
Aim

A simple and reliable method for diagnosing COVID 19 infections is the needed. The role of saliva in the transmission of the infection has already been established.

Method

Saliva and nasopharyngeal swabs from patients suspected to have COVID 19 infections were taken simultaneously, and the results of the RT-PCR were compared.

Result

Total 405 samples were collected, of which 250 males and 155 females. In the 391 samples included for analysis, 370 (94.63%) samples were found to have concordance results, and 21 (5.37%) samples had discordant results.

Conclusion

The use of saliva to diagnose COVID 19 infection is reliable, and its use can be recommended.

Keywords:
Saliva
Nasopharyngeal swab
COVID 19
SARS-CoV 2
Abbreviations:
COVID-19
RTPCR
NPS
Ct
SARS
MERS
LR
Resumen
Objetivo

Un método simple y confiable para diagnosticar infecciones por COVID 19 es necesario. Ya se ha establecido el papel de la saliva en la transmisión de la infección.

Método

Se tomaron simultáneamente hisopos de saliva y nasofaríngeos de pacientes con sospecha de infección por COVID 19 y se compararon los resultados de la RT-PCR.

Resultado

Se recogieron 405 muestras, de las cuales 250 hombres y 155 mujeres. En las 391 muestras incluidas para el análisis, se encontró que 370 (94,63%) muestras tenían resultados de concordancia y 21 (5,37%) muestras tenían resultados discordantes.

Conclusión

El uso de la saliva para diagnosticar la infección por COVID 19 es confiable y se puede recomendar su uso.

Palabras clave:
Saliva
Hisopado nasofaríngeo
COVID-19
SARS-CoV-2

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