TY - JOUR T1 - Probiotics and Helicobacter pylori infection JO - Medicina Universitaria T2 - AU - Praitano M,Massimiliano AU - Iacono,Salvatore AU - Francavilla,Ruggiero SN - 16655796 UR - https://www.elsevier.es/en-revista-medicina-universitaria-304-articulo-probiotics-helicobacter-pylori-infection-X1665579612844286 AB - Approximately 50% of the world population is infected with Helicobacter pylori (H. pylori), with the highest prevalence rates in developing countries. The current guidelines suggest the use of triple therapy as first choice treatment of H. pylori infection, although the eradication failure rate is more than 30%. Current interest in probiotics as therapeutic agents against H. pylori is stimulated by the increasing resistance of pathogenic bacteria to antibiotics, thus the interest for alternative therapies is a real actual topic. Available data in children indicate that probiotics seems to be efficacious for the prevention of antibiotic associated side-effects, and might be helpful for the prevention of H. pylori complications by decreasing H. pylori density, gastritis, and for the prevention of H. pylori colonization or re-infection by inhibiting adhesion to gastric epithelial cells. There is no clear evidence that probiotics may increase the H. pylori eradication rate. ER -