TY - JOUR T1 - Use of Magnetic Resonance Imaging in the Evaluation of Mediastinal and Systemic Disease in Lymphoma. A Systematic Review JO - Open Respiratory Archives T2 - AU - Pereiro-Brea,Tara AU - Ruano-Raviña,Alberto AU - Golpe-Gómez,Antonio AU - Martínez de Alegría,Anxo AU - Carreira-Villamor,José Martín AU - Abuín-Blanco,Aitor AU - Valdés,Luis SN - 26596636 M3 - 10.1016/j.opresp.2020.03.002 DO - 10.1016/j.opresp.2020.03.002 UR - https://www.elsevier.es/en-revista-open-respiratory-archives-11-articulo-use-magnetic-resonance-imaging-in-S2659663620300114 AB - PurposeThe aim of this study is to assess the diagnostic value of magnetic resonance imaging (MRI), alone or combined with positron emission tomography (PET), for evaluation of mediastinal disease in lymphoma in comparison with PET/computed tomography (CT). Material and methodsEighteen prospective studies with sample size ranging between 17 and 140 patients were included in this analysis. MRI, regardless of the sequence obtained, where used for the evaluation of lymphoma. Histopathology results and clinical or imaging follow-up were used as the reference standard. Studies were excluded if the sample size was less than 15 cases or if less than 15 lymph nodes assessment were presented. Papers not reporting sufficient data were also excluded. ResultsAs compared to PET/CT, MRI proved to be an alternative to use in evaluation of mediastinal disease of lymphoma. MRI has high sensitivity and specificity for nodal and extranodal involvement in lymphoma and the agreement between MRI with the standard technique was high. The ALARA principle reinforces these findings because it is a radiation-free technique and its use is preferred in young population at risk of being subjected to several studies. ConclusionMRI seems to be a promising and free-radiation alternative due to its high sensitivity and specificity, as well as its high level of agreement with the standard reference. This suggests that MRI could play a significant role in lymphoma study. ER -