TY - JOUR T1 - Selective sentinel lymph node biopsy in papillary thyroid carcinoma in patients with no preoperative evidence of lymph node metastasis JO - Endocrinología, Diabetes y Nutrición (English ed.) T2 - AU - González,Óscar AU - Zafon,Carles AU - Caubet,Enric AU - García-Burillo,Amparo AU - Serres,Xavier AU - Fort,José Manuel AU - Mesa,Jordi AU - Castell,Joan AU - Roca,Isabel AU - Ramón y Cajal,Santiago AU - Iglesias,Carmela SN - 25300180 M3 - 10.1016/j.endien.2017.10.001 DO - 10.1016/j.endien.2017.10.001 UR - https://www.elsevier.es/en-revista-endocrinologia-diabetes-nutricion-english-ed--413-articulo-selective-sentinel-lymph-node-biopsy-S2530018017301348 AB - IntroductionLymphadenectomy is recommended during surgery for papillary thyroid carcinoma when there is evidence of cervical lymph node metastasis (therapeutic) or in high-risk patients (prophylactic) such as those with T3 and T4 tumors of the TNM classification. Selective sentinel lymph node biopsy may improve preoperative diagnosis of nodal metastases. ObjectiveTo analyze the results of selective sentinel lymph node biopsy in a group of patients with papillary thyroid carcinoma and no evidence of nodal involvement before surgery. Patients and methodA retrospective, single-center study in patients with papillary thyroid carcinoma and no clinical evidence of lymph node involvement who underwent surgery between 2011 and 2013. The sentinel node was identified by scintigraphy. When the sentinel node was positive, the affected compartment was removed, and when sentinel node was negative, central lymph node dissection was performed. ResultsForty-three patients, 34 females, with a mean age of 52.3 (±17) years, were enrolled. Forty-six (27%) of the 170 SNs resected from 24 (55.8%) patients were positive for metastasis. In addition, 94 (15.6%) out of the 612 lymph nodes removed in the lymphadenectomies were positive for metastases. Twelve of the 30 (40%) low risk patients (cT1N0 and cT2N0) changed their stage to pN1, whereas 12 of 13 (92%) high risk patients (cT3N0 and cT4N0) changed to pN1 stage. ConclusionsSelective sentinel lymph node biopsy changes the stage of more than 50% of patients from cN0 to pN1. This confirms the need for lymph node resection in T3 and T4 tumors, but reveals the presence of lymph node metastases in 40% of T1–T2 tumors. ER -