TY - JOUR T1 - Inflammation and atherogenic markers in patients with type 2 diabetes mellitus JO - Clínica e Investigación en Arteriosclerosis (English Edition) T2 - AU - Maravilla Domínguez,María Aurora AU - Zermeño González,María de Lourdes AU - Zavaleta Muñiz,Elias Roberto AU - Montes Varela,Verónica Adriana AU - Irecta Nájera,Cesar Antonio AU - Fajardo Robledo,Nicté Selene AU - Zavaleta Muñiz,Soraya Amalí SN - 25299123 M3 - 10.1016/j.artere.2022.05.001 DO - 10.1016/j.artere.2022.05.001 UR - https://www.elsevier.es/en-revista-clinica-e-investigacion-arteriosclerosis-english-415-articulo-inflammation-atherogenic-markers-in-patients-S2529912322000213 AB - Type two diabetes mellitus (T2DM) is characterized by a chronic inflammation status. Altered markers such as lipid concentrations are usually found in this disease. Elevated inflammation markers have been described such as cytokines (interleukin 6, tumour necrosis factor-alpha, and IL-8). However, there is a lack of information about the behaviour of the neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), lipid coefficients, and atherogenic index in T2DM. ObjectiveTo describe the atherogenic and inflammation parameters in a group of patients with T2DM. Materials and methodsA total of 42 patients with T2DM were included, all patients were surveyed on clinic history (disease history,comorbidity, smoking, and other relevant variables), measurements of haematological, biochemical,and anthropometric parameters were taken and atherogenic coefficients and inflammation ratios were calculated. ResultsInflammation markers such as interleukin 6 and 8, necrosis tumour factor, and NLR were elevated. Of the patients, 88% were classified as high risk according to the atherogenic index. Former smokers had lower levels of IL-8 and higher NLR than non-smokers. ConclusionThe atherogenic and inflammation markers such as atherogenic index, IL- 8, and NLR make it possible to identify a subgroup of patients that are at risk of severe complications and mortality. ER -