TY - JOUR T1 - Microbiological characteristics and patterns of resistance in prosthetic joint infections in a referral hospital JO - Cirugía y Cirujanos (English Edition) T2 - AU - Ortega-Peña,Silvestre AU - Colín-Castro,Claudia AU - Hernández-Duran,Melissa AU - López-Jácome,Esaú AU - Franco-Cendejas,Rafael SN - 24440507 M3 - 10.1016/j.circen.2015.10.002 DO - 10.1016/j.circen.2015.10.002 UR - https://www.elsevier.es/en-revista-cirugia-cirujanos-english-edition--237-articulo-microbiological-characteristics-patterns-resistance-in-S2444050715001060 AB - BackgroundThe prosthetic joint infection is the most feared and catastrophic complication for cause severe physical damage to patients and, generates high economic costs. ObjectivesTo describe the microbiological characteristics and to determine the resistance pattern in prosthetic joint infections in a reference hospital in Mexico. Material and methodsPatients whose prosthetic devices were withdrawn due to suspicion of septic and aseptic loosening were included. Cultures were performed to identify microorganisms and susceptibility analysis. ResultsOf the 111 patients included, 55% were diagnosed with prosthetic joint infection, with the most frequent prosthesis being of the hip (43%). Positive cultures were obtained in 97% of the infected cases, of which 75% were monomicrobial infections. The most frequent bacterial species isolated were: Staphylococcus epidermidis (31%), Enterococcus faecalis (16%), Staphylococcus aureus (13%), and Escherichia coli (8%). The resistance patterns for the Staphylococcus genus were: oxacillin (79%), erythromycin (45%) and ciprofloxacin (37%). Enterococcus faecalis showed a high percentage of resistance to erythromycin and clindamycin (86%), and fluoroquinolones (43%). The large majority (86%) of Escherichia coli were extended spectrum beta-lactamases positive, in addition to having high resistance to fluoroquinolones (86%), trimethoprim/sulfamethoxazole (86%) and gentamicin (72%). ConclusionThe microbiological characteristics found in prosthetic joint infections vary according to the hospitals. In this series, a high proportion of coagulase-negative Staphylococci and Enterococcus spp. were found, as well as a high bacterial resistance. ER -