TY - JOUR T1 - Large Colorectal Lesions: Evaluation and Management JO - GE - Portuguese Journal of Gastroenterology T2 - AU - dos Santos,Carlos Eduardo Oliveira AU - Pereira-Lima,Júlio Carlos AU - Onófrio,Fernanda de Quadros SN - 23414545 M3 - 10.1016/j.jpge.2016.01.001 DO - 10.1016/j.jpge.2016.01.001 UR - https://www.elsevier.es/en-revista-ge-portuguese-journal-gastroenterology-347-articulo-large-colorectal-lesions-evaluation-management-S2341454516000107 AB - In the last years, a distinctive interest has been raised on large polypoid and non-polypoid colorectal tumors, and specially on flat neoplastic lesions ≥20mm tending to grow laterally, the so called laterally spreading tumors (LST). Real or virtual chromoendoscopy, endoscopic ultrasound or magnetic resonance should be considered for the estimation of submucosal invasion of these neoplasms. Lesions suitable for endoscopic resection are those confined to the mucosa or selected cases with submucosal invasion ≤1000μm. Polypectomy or endoscopic mucosal resection remain a first-line therapy for large colorectal neoplasms, whereas endoscopic submucosal dissection in high-volume centers or surgery should be considered for large LSTs for which en bloc resection is mandatory. ER -