TY - JOUR T1 - Cochleotoxicity monitoring protocol JO - Acta Otorrinolaringológica Española T2 - AU - Ferreira Penêda,José AU - Barros Lima,Nuno AU - Ribeiro,Leandro AU - Helena,Diamantino AU - Domingues,Bruno AU - Condé,Artur SN - 21735735 M3 - 10.1016/j.otoeng.2018.03.001 DO - 10.1016/j.otoeng.2018.03.001 UR - https://www.elsevier.es/en-revista-acta-otorrinolaringologica-espanola-402-articulo-cochleotoxicity-monitoring-protocol-S2173573518300243 AB - IntroductionCochlear damage is frequent in long-term aminoglycosides therapy or chemotherapeutic treatments with platinum-based agents. Despite its prevalence, it is currently underestimated and underdiagnosed. A monitoring protocol is vital to the early detection of cochleotoxicity and its implementation is widely encouraged in every hospital unit. Our aim was to elaborate a cochleotoxicity monitoring protocol for patients treated with platinum compounds or aminoglycosides antibiotics. MethodsPubMed® database was searched using terms relevant to drug cochleotoxicity in order to identify the most adequate protocol. Several articles and guidelines influenced our decision. ResultsThere is no consensus on a universal monitoring protocol. Its formulation and application rely heavily on available resources and personnel. High-frequency audiometry and otoacoustic emissions play an important role on early detection of cochleotoxicity caused by aminoglycoside antibiotics and platinum compounds. ConclusionA cochleotoxicity monitoring protocol consisting on an initial evaluation, treatment follow-up and post-treatment evaluation is proposed. ER -