TY - JOUR T1 - Prevalence of impaired fasting glucose and type 1 and 2 diabetes mellitus in a large nationwide working population in Spain JO - Endocrinología y Nutrición (English Edition) T2 - AU - Reviriego,Jesús AU - Vázquez,Luis Alberto AU - Goday,Albert AU - Cabrera,Martha AU - García-Margallo,María Teresa AU - Calvo,Eva SN - 21735093 M3 - 10.1016/j.endoen.2016.04.007 DO - 10.1016/j.endoen.2016.04.007 UR - https://www.elsevier.es/en-revista-endocrinologia-nutricion-english-edition--412-articulo-prevalence-impaired-fasting-glucose-type-S2173509316300216 AB - IntroductionTo report the prevalence of impaired fasting glucose (IFG), undiagnosed and diagnosed diabetes, and their association to occupational categories in a representative sample of working population in Spain. Materials and methodsA cross-sectional study of workers who attended routine medical check-ups from January 2007 to December 2007. A structured questionnaire was completed, and physical examinations and routine serum biochemical tests were performed. IFG was defined as fasting glucose levels ranging from 100 to 125mg/dl with no diagnosis of T1DM or T2DM; T1DM was defined as previous diagnosis of T1DM; and T2DM as previous diagnosis of T2DM, treatment with oral antidiabetic drugs or insulin or fasting glucose levels ≥126mg/dl, according to ADA criteria. ResultsOf the 371,997 participants (median age 35 [interquartile range 29–44] years), 72.4% were male. Raw prevalence rates (95% CI) of IFG, undiagnosed (UKDM), and previously known type 2 (KDM2) and type 1 (KDM1) diabetes were 10.4% (10.3–10.5%), 1.3% (1.2–1.3%), 1.1% (1.1–1.2%), and 0.3% (0.3–0.3%), respectively. With the exception of KDM1, prevalence of these conditions increased with age and was greater among manual/blue-collar workers (12.1%, 1.5%, 1.3% and 0.3%, respectively) as compared to non-manual/white-collar workers (7.3%, 0.8%, 0.8% and 0.3%, respectively). Age- and sex-adjusted prevalence rates of IFG, UKDM and KDM2 were 13.1%, 2.0% and 2.4%, respectively. DiscussionIn this sample of Spanish working population, impaired glycemic profiles were common. Prevalence rates of IFG and T2DM were high among blue-collar workers (except for T1DM). These data emphasize the need for earlier structured preventive schemes. ER -