TY - JOUR T1 - Incidence rate of adverse drug effects in a hospital emergency unit and its associated factors JO - Farmacia Hospitalaria (English Edition) T2 - AU - Ramos Linares,S. AU - DíazRuiz,P. AU - Mesa Fumero,J. AU - Núñez Díaz,S. AU - Suárez González,M. AU - Callejón Callejón,G. AU - Tévar Alfonso,E. AU - Plasencia García,I. AU - Martín Conde,J.A. AU - Hardisson de la Torre,A. AU - Aguirre-Jaime,A. SN - 21735085 M3 - 10.1016/S2173-5085(10)70020-4 DO - 10.1016/S2173-5085(10)70020-4 UR - https://www.elsevier.es/en-revista-farmacia-hospitalaria-english-edition--221-articulo-incidence-rate-adverse-drug-effects-S2173508510700204 AB - IntroductionAdverse drug effects (ADE) are the reason for 0.86% to 38.2% of emergency hospital admissions, and a large percentage of them are avoidable. Rational prescription and pharmacotherapy monitoring reduce the appearance of such health problems. MethodStudy performed in a tertiary hospital emergency unit with patients selected using a two-phase random sample. The information was obtained from a validated questionnaire and from the clinical history. The data were grouped according to the following cause-effect schema: 1-Potential risk factors for an ADE. 2-Effects likely to be caused by drugs. 3-Consequences of ADE. 4-Potential confounding factors. The information obtained was evaluated by four independent evaluators using the Dader method. ResultsEight hundred forty patients were included in the study, and 33% of them came to the emergency unit due to an ADE. ADE were more frequently observed in female patients, those with higher drug consumption, older patients, those with an underlying illness and in those from underprivileged backgrounds. The factors determining risk of an ADE are the quantity of drugs consumed, sex and the health practices index. DiscussionOne third of emergency hospital admissions were due to ADE, and these were associated with the same factors found in other studies (number of drugs consumed, female sex, age and social background). In addition, we observed that ADE are predominant in patients with low values on the health practices index, and in those with underlying illnesses. ER -