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Assessing apathy: The use of the Apathy Evaluation Scale in first episode psychosis

Published online by Cambridge University Press:  16 April 2020

Ann Faerden ,
Ragnar Nesvåg ,
Elizabeth Ann Barrett ,
Ingrid Agartz ,
Arnstein Finset ,
Svein Friis ,
Jan Ivar Rossberg  and
Ingrid Melle
Ann Faerden*
Affiliation:
Section for Psychosis Research, Division of Psychiatry, Building 49, Ullevål University Hospital, Krikeveien 166, 0407Oslo, Norway
Ragnar Nesvåg
Affiliation:
Diakonhjemmet Hospital, 0319Oslo, Norway
Elizabeth Ann Barrett
Affiliation:
Aker University Hospital, 0514Oslo, Norway
Ingrid Agartz
Affiliation:
Diakonhjemmet Hospital, 0319Oslo, Norway Institute of Psychiatry, University of Oslo, 0318Oslo, Norway
Arnstein Finset
Affiliation:
Institute of Behavioural Sciences in Medicine, University of Oslo, 0317Oslo, Norway
Svein Friis
Affiliation:
Section for Psychosis Research, Division of Psychiatry, Building 49, Ullevål University Hospital, Krikeveien 166, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, 0318Oslo, Norway
Jan Ivar Rossberg
Affiliation:
Section for Psychosis Research, Division of Psychiatry, Building 49, Ullevål University Hospital, Krikeveien 166, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, 0318Oslo, Norway
Ingrid Melle
Affiliation:
Section for Psychosis Research, Division of Psychiatry, Building 49, Ullevål University Hospital, Krikeveien 166, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, 0318Oslo, Norway
*
*Corresponding author. Tel.: +47 22118460; fax: +47 23027333. E-mail address: ann.farden@medisin.uio.no (A. Faerden).
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Abstract

Background

Recently there has been a renewed interest in defining the boundaries and subdomains of the negative syndrome in schizophrenia and new scales have been asked for. Apathy is one of the symptoms in focus. The Apathy Evaluation Scale (AES) with its clinical version (AES-C) is one of the most used scales in an interdisciplinary context, but it has never previously been used in a population with first episode psychosis. The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS).

Methods

A total of 104 patients with first episode psychosis from the ongoing Thematic Organized Psychosis Research (TOP) study were included.

Results

A factor analysis of the AES-C identified three subscales: Apathy, Insight and Social Contacts. Only the Apathy subscale showed satisfactory psychometric properties and showed acceptable convergent and discriminate properties by correlating strongly with the apathy-related items of the PANSS.

Conclusions

This study shows that the AES-C measures more than one dimension. The main factor, the Apathy subscale, can however be used to assess apathy in first episode psychosis patients in the ongoing work of refining the subdomains of the negative syndrome.

Keywords

First episode psychosisNegative syndromeNegative symptomsApathyPsychometric rating scaleAssessment
Type
Original articles
Information
European Psychiatry , Volume 23 , Issue 1 , January 2008 , pp. 33 - 39
Copyright
Copyright © Elsevier Masson SAS 2008

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References

Altamura, A.C., Bassetti, R., Sassella, F., Salvadori, D., Mundo, E.Duration of untreated psychosis as a predictor of outcome in first-episode schizophrenia: a retrospective study. Schizophr Res 2001;52(1–2):29–36.CrossRefGoogle ScholarPubMed
American Psychiatric Association. Diagnostic and statistical manual of mental disorders DSM IV. 4th ed.Washington DC: American Psychiatric Association; 1994.Google Scholar
Andersson, S., Krogstad, J.M., Finset, A.Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reaction. Psychol Med 1999;29(2):447–456.CrossRefGoogle Scholar
Andreasen, N.C.Schizophrenia: Positive and negative symptoms and syndromes. Basel: Modern Problems of Pharmocopsychiatry; 1990.Google Scholar
Baudic, S., Maison, P., Dolbeau, G., Boisse, M.F., Bartolomeo, P., Dalla, B.G.et al.Cognitive impairment related to apathy in early Huntington's disease. Dement Geriatr Cogn Disord 2006;21(5–6):316–321.CrossRefGoogle ScholarPubMed
Blanchard, J.J., Cohen, A.S.The structure of negative symptoms within schizophrenia: implications for assessment. Schizophr Bull 2005 Oct 27.Google ScholarPubMed
Bleuler, E.Dementia preacox or the group of schizophrenias. New York: International Universities Press; 1950.Google Scholar
Bower, F.L., McCullough, C.S., Pille, B.L.Synthesis of research findings regarding Alzheimer's disease: part III, Caregiver burden and care settings. Online J Knowl Synth Nurs 2002;9:5.Google ScholarPubMed
Clarke, D.E., Reekum, R., Simard, M., Streiner, D.L., Freedman, M., Conn, D.Apathy in dementia: an examination of the psychometric properties of the apathy evaluation scale. J Neuropsychiatry Clin Neurosci 2007;19(1):57–64.CrossRefGoogle ScholarPubMed
Cummings, J.L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D.A., Gornbein, J.The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994;44(12):2308–2314.CrossRefGoogle ScholarPubMed
Earnst, K.S., Kring, A.M.Construct validity of negative symptoms: an empirical and conceptual review. Clin Psychol Rev 1997;17(2):167–189.CrossRefGoogle ScholarPubMed
Emsley, R., Rabinowitz, J., Torreman, M.The factor structure for the Positive and Negative Syndrome Scale (PANSS) in recent-onset psychosis. Schizophr Res 2003;61(1):47–57.CrossRefGoogle Scholar
Erhart, S.M., Marder, S.R., Carpenter, W.T.Treatment of schizophrenia negative symptoms: future prospects. Schizophr Bull 2006;32(2):234–237.CrossRefGoogle ScholarPubMed
Finset, A., Andersson, S.Coping strategies in patients with acquired brain injury: relationships between coping, apathy, depression and lesion location. Brain Inj 2000;14(10):887–905.Google ScholarPubMed
Jones, S.H., Thornicroft, G., Coffey, M., Dunn, G.A brief mental health outcome scale-reliability and validity of the Global Assessment of Functioning (GAF). Br J Psychiatry 1995;166(5):654–659.CrossRefGoogle Scholar
Kalechstein, A.D., Newton, T.F., Leavengood, A.H.Apathy syndrome in cocaine dependence. Psychiatry Res 2002;109(1):97–100.CrossRefGoogle ScholarPubMed
Kay, S.R., Fiszbein, A., Opler, L.A.The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987;13(2):261–276.CrossRefGoogle Scholar
Kiang, M., Christensen, B.K., Remington, G., Kapur, S.Apathy in schizophrenia: clinical correlates and association with functional outcome. Schizophr Res 2001;63(1–2):79–88.CrossRefGoogle Scholar
Kirkpatrick, B., Fenton, W.S., Carpenter, W.T. Jr., Marder, S.R.The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull 2006;32(2):214–219.CrossRefGoogle ScholarPubMed
Kirsch-Darrow, L., Fernandez, H.H., Marsiske, M., Okun, M.S., Bowers, D.Dissociating apathy and depression in Parkinson disease. Neurology 2006;67(1):33–38.CrossRefGoogle ScholarPubMed
Kraepelin, E.Reprint 1919 English translated edition. In: Robert, E., editors. Dementia praecox and paraphrenia. Huntington. New York: Krieger Publishing Co Inc.; 1971.Google Scholar
Lueken, U., Seidl, U., Volker, L., Schweiger, E., Kruse, A., Schroder, J.Development of a short version of the Apathy Evaluation Scale specifically adapted for demented nursing home residents. Am J Geriatr Psychiatry 2007;15(5):376–385.CrossRefGoogle Scholar
Malla, A.K., Takhar, J.J., Norman, R.M., Manchanda, R., Cortese, L., Haricharan, R.et al.Negative symptoms in first episode non-affective psychosis. Acta Psychiatr Scand 2002;105(6):431–439.CrossRefGoogle ScholarPubMed
Marin, R.S.Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 1991;3(3):243–254.Google ScholarPubMed
Marin, R.S., Biedrzycki, R.C., Firinciogullari, S.Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res 1991;38(2):143–162.CrossRefGoogle ScholarPubMed
Marin, R.S., Fogel, B.S., Hawkins, J., Duffy, J., Krupp, B.Apathy: a treatable syndrome. J Neuropsychiatry Clin Neurosci 1995;7(1):23–30.Google ScholarPubMed
Moller, H.J., Bottlender, R., Gross, A., Hoff, P., Wittmann, J., Wegner, U.et al.The Kraepelinian dichotomy: preliminary results of a 15-year follow-up study on functional psychoses: focus on negative symptoms. Schizophr Res 2002;56(1–2):87–94.CrossRefGoogle ScholarPubMed
Overall, J.E., Gorham, D.R.The Brief Psychaitric rating Scale (BPRS): recent development in ascertainment and scaling. Psychopharmacol Bull 1988;24:97–99.Google Scholar
Peralta, V., Cuesta, M.J.How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment. Schizophr Res 2001;49(3):269–285.CrossRefGoogle ScholarPubMed
Richard, I.H.Apathy does not equal depression in Parkinson disease: why we should care. Neurology 2006;67(1):10–11.CrossRefGoogle Scholar
Robert, P.H., Clairet, S., Benoit, M., Koutaich, J., Bertogliati, C., Tible, O.et al.The apathy inventory: assessment of apathy and awareness in Alzheimer's disease, Parkinson's disease and mild cognitive impairment. Int J Geriatr Psychiatry 2002;17(12):1099–1105.CrossRefGoogle ScholarPubMed
Robert, P.H., Verhey, F.R., Byrne, E.J., Hurt, C., De Deyn, P.P., Nobili, F.et al.Grouping for behavioral and psychological symptoms in dementia: clinical and biological aspects. Consensus paper of the European Alzheimer disease consortium. Eur Psychiatry 2005;20(7):490–496.CrossRefGoogle ScholarPubMed
Selten, J.P., van de Wiersma, D.Distress attributed to negative symptoms in schizophrenia. Schizophr Bull 2000;26(3):737–744.CrossRefGoogle Scholar
Starkstein, S.E., Petracca, G., Chemerinski, E., Kremer, J.Syndromic validity of apathy in Alzheimer's disease. Am J Psychiatry 2001;158(6):872–877.CrossRefGoogle ScholarPubMed
Stout, J.C., Ready, R.E., Grace, J., Malloy, P.F., Paulsen, J.S.Factor analysis of the frontal systems behavior scale (FrSBe). Assessment 2003;10(1):79–85.CrossRefGoogle Scholar
Toomey, R., Kremen, W.S., Simpson, J.C., Samson, J.A., Seidman, L.J., Lyons, M.J.et al.Revisiting the factor structure for positive and negative symptoms: evidence from a large heterogeneous group of psychiatric patients. Am J Psychiatry 1997;154(3):371–377.Google ScholarPubMed
van Reekum, R., Stuss, D.T., Ostrander, L.Apathy: why care? J Neuropsychiatry Clin Neurosci 2005;17(1):7–19.CrossRefGoogle ScholarPubMed
Ventura, J., Liberman, R.P., Green, M.F., Shaner, A., Mintz, J.Training and quality assurance with the Structured Clinical Interview for DSM-IV (SCID-I/P). Psychiatry Res 1998;79(2):163–173.CrossRefGoogle Scholar
Ventura, J., Nuechterlein, K.H., Subotnik, K.L., Gutkind, D., Gilbert, E.A.Symptom dimensions in recent-onset schizophrenia and mania: a principal components analysis of the 24-item Brief Psychiatric Rating Scale. Psychiatry Res 2000;97(2–3):129–135.CrossRefGoogle ScholarPubMed
Yung, A.R., Phillips, L.J., Yuen, H.P., Francey, S.M., McFarlane, C.A., Hallgren, M.et al.Psychosis prediction: 12-month follow up of a high-risk (“prodromal”) group. Schizophr Res 2003;60(1):21–32.CrossRefGoogle ScholarPubMed
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