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© Thomson Reuters, Journal Citation Reports, 2016

Med Clin 2000;115:343-6 - DOI: 10.1016/S0025-7753(00)71552-1
Tratamiento de la embolia pulmonar submasiva con heparina de bajo peso molecular
Manuel Monreal Bosch,
Profesor titular de Medicina. Universidad Autónoma de Barcelona. Servicio de Medicina Interna. Hospital Universitari Germans Trias i Pujol. Badalona. Barcelona.
Recibido 21 marzo 2000, Aceptado 30 junio 2000
Palabras clave
Embolia pulmonar, Tratamiento, Trombosis venosa, Heparina de bajo peso molecular, Supervivencia
El Texto completo solo está disponible en PDF
Referencias Bibliográficas
B. Lindblad,A. Eriksson,D. Bergqvist
Autopsy-verified pulmonary embolism in a surgical department: analysis of the period from 1951 to 1988
Br J Surg, 78 (1991), pp. 849-852
B. Lindblad,N.H. Sternby,D. Bergqvist
Incidence of venous thromboembolism verified by necropsy over 30 years
Br Med J, 302 (1991), pp. 709-711
F.A. Anderson,H.B. Wheeler,R.J. Goldberg,D.W. Hosmer,A. Forcier
The prevalence of risk factors for venous thromboembolism among hospital patients
Arch Intern Med, 152 (1992), pp. 1660-1664
M. Nordstrom,B. Lindblad,D. Bergqvist,T. Kjellstrom
A prospective study of the incidence of deep-vein thrombosis within a defined urban population
J Intern Med, 152 (1992), pp. 155-160
S.Z. Goldhaber,L. Visani,M. De Rosa
for ICOPER. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER)
Lancet, 353 (1999), pp. 1386-1389
M. Monreal,J. Ruiz,R. Salvador,J. Morera,A. Arias
Recurrent pulmonary embolism. A prospective study
Chest, 95 (1989), pp. 976-979
M. Monreal,E. Lafoz,J. Ruiz,J.M. Callejas,A. Arias
Recurrent pulmonary embolism in patients treated because of acute venous thromboembolism: a prospectiva study
Eur J Vasc Surg, 8 (1994), pp. 584-589
J.D. Douketis,C. Kearon,S. Bates,E.K. Duku,J.S. Ginsberg
Risk of fatal pulmonary embolism in patients with treated venous thromboembolism
JAMA, 279 (1998), pp. 458-462
The Columbus Investigators. Low molecular weight heparin is an effective and safe treatment for venous thromboembolism
N Engl J Med, 337 (1997), pp. 657-662 http://dx.doi.org/10.1056/NEJM199709043371001
S. Lopaciuk,A.J. Meissner,S. Filipecki,K. Zawilska,J. Sowier,L. Ciesielski
Subcutaneous low molecular weight heparin versus subcutaneous unfractionated heparin in the treatment of deepvein thrombosis: a Polish multicentre trial
Thromb Haemost, 68 (1992), pp. 14-18
R.D. Hull,G.E. Raskob,J. Hirsh,R.M. Jay,J.R. Leclerc,W.H. Geerts
Continuous intravenous heparin compared with intermittent sucutaneous heparin in the initial treatment of proximalvein thrombosis
N Engl J Med, 315 (1986), pp. 1109-1114 http://dx.doi.org/10.1056/NEJM198610303151801
R.D. Hull,G.E. Raskob,D. Rosenbloom,A.A. Panju,P. Brill-Edwards,J.S. Ginsberg
Heparin for 5 days as compared with 10 days in the initial treatment of proximal venous thrombosis
N Engl J Med, 322 (1990), pp. 1260-1264 http://dx.doi.org/10.1056/NEJM199005033221802
A Collaborative European Multicentre Study. A randomised trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis
Thromb Haemost, 65 (1991), pp. 251-256
R.D. Hull,G.E. Raskob,G.F. Pineo,D. Green,A.A. Trowbridge,C.G. Elliott
Subcutaneous low-molecular-weight heparina compared with continuous heparin in the treatment of proximal-vein thrombosis
N Engl J Med, 326 (1992), pp. 975-982 http://dx.doi.org/10.1056/NEJM199204093261502
G. Simonneau,B. Charbonnier,H. Decoussus,B. Planchon,J. Ninet,P. Sie
Sucutaneous low-molecular-weight heparin compared with continuous intravenous unfractionated heparin in the treatment of proximal deep vein thrombosis
Arch Intern Med, 153 (1993), pp. 1541-1546
M. Levine,M. Gent,J. Hirsh,J. Leclerc,D. Anderson,J. Weitz
A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis
N Engl J Med, 334 (1996), pp. 677-681 http://dx.doi.org/10.1056/NEJM199603143341101
D.P.M. Brandjes,H. Heijboer,H.R. Buller,M. De Rijk,H. Jagt,J.W. Ten Cate
Acenocoumarol and heparin compared with acenocoumarol alone in the initial treatment of proximal-vein thrombosis
N Engl J Med, 327 (1992), pp. 1485-1489 http://dx.doi.org/10.1056/NEJM199211193272103
M.V. Huisman,H.R. Buller,J.W. Ten Cate,J. Vreeken
Serial impedance plethysmography for suspected deep venous thrombosis in outpatients
N Engl J Med, 314 (1986), pp. 823-828 http://dx.doi.org/10.1056/NEJM198603273141305
R. Hull,T. Delmore,C. Carter,J. Hirsh,E. Genton,M. Gent
Adjusted subcutaneous heparin versus warfarin sodium in the long-term treatment of venous thrombisis
N Engl J Med, 306 (1982), pp. 189-194 http://dx.doi.org/10.1056/NEJM198201283060401
P. Prandoni,A.W.A. Lensing,H.R. Buller,M. Carta,A. Cogo,M. Vigo
Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deepvein thrombosis
Lancet, 339 (1992), pp. 441-445
M.M.W. Koopman,P. Prandoni,F. Piovella,P.A. Ockelford,D.P. Brandjes,J. Van der Meer
Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home
N Engl J Med, 334 (1996), pp. 682-687 http://dx.doi.org/10.1056/NEJM199603143341102
R. Hull,T. Delmore,E. Genton,J. Hirsh,M. Gent,D. Sackett
Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis
N Engl J Med, 301 (1979), pp. 855-885 http://dx.doi.org/10.1056/NEJM197910183011602
R. Hull,J. Hirsh,R. Jay,C. Carter,C. England,M. Gent
Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis
N Engl J Med, 307 (1982), pp. 1676-1681 http://dx.doi.org/10.1056/NEJM198212303072704
R.D. Hull,J. Hirsh,C.J. Carter,R. Jay,P.A. Ockelford,H.R. Buller
Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis
Ann Intern Med, 102 (1985), pp. 21-28
P. Lindmarke,M. Holmstrom
Comparison of oncedaily subcutaneous Fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis
Haemost, 72 (1994), pp. 186-190
M.N. Levine,J. Hirsh,M. Gent,A.G. Turpie,J. Weitz,J. Ginsberg
Optimal duration of oral anticoagulant therapy: a randomized trial comparing four weks three months of warfarin in patients with proximal deep veint thrombosis
Thromb Haemost, 74 (1995), pp. 606-611
C.I. Lagerstedt,C.G. Olsson,B.O. Fagher,B.W. Oqvist,U. Albrechtsson
Need for long-term anticoagulant treatment in symptomatic calf-vein thrombosis
Lancet, 2 (1985), pp. 515-518
S. Schulman,D. Lockner,A. Juhlin-Dannfelt
The duration of oral anticoagulation after deep vein thrombosis
Acta Med Scand, 217 (1985), pp. 547-552
G. Bratt,W. Aberg,M. Johansson,E. Tornebohm,S. Granqvist,D. Lockner
Two daily sucutaneous injections of Fragmin as compared with intravenous standard heparin in the treatment of deep veint thrombosis (DVT)
Thromb Haemost, 64 (1990), pp. 506-510
G. Simonneau,H. Sors,B. Charbonnier,Y. Page,J.P. Laaban,R. Azarian
A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism
N Engl J Med, 337 (1997), pp. 663-669 http://dx.doi.org/10.1056/NEJM199709043371002
R.D. Hull,G.E. Raskob,J.S. Ginsberg,A.A. Panju,P. Brill-Edwards,G. Coates
A noninvasive strategy for the treatment of patients with suspected pulmonary embolism
Arch Intern Med, 154 (1994), pp. 289-297
R.D. Hull,J. Hirsh,C.J. Carter,R.M. Jay,P.E. Dood,P.A. Ockelford
Pulmonary angiography, ventilation lung scanning, and venography for clinically suspected pulmonary embolism with abnormal perfusion lung scan
Ann Intern Med, 98 (1983), pp. 891-899
J.L. Carson,K.A. Kelley,A. Duff,J.G. Weg,W.J. Fulkerson,H.I. Palersky
The clinical course of pulmonary embolism
N Engl J Med, 326 (1992), pp. 891-899
L.Q. Rogers,C.L. Lutcher
Streptokinase therapy for deep vein thrombosis: a comprehensive review of the english literature
Am J Med, 88 (1990), pp. 389-395
J.J. O'Meara,R.A. McNutt,A.T. Evans,S.W. Moore,S.M. Downs
A decision analysis of streptokinase plus heparin as compared with heparin alone for deep-vein thrombosis
N Engl J Med, 330 (1994), pp. 1864-1869 http://dx.doi.org/10.1056/NEJM199406303302605
R. Collins,A. Sgrimgeour,S. Yusuf,R. Peto
Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of sucbutaneous heparin
N Engl J Med, 318 (1988), pp. 1162-1173 http://dx.doi.org/10.1056/NEJM198805053181805
M.T. Nurmohamed,F.R. Rosendaal,H.R. Buller,E. Dekker,D.W. Hommes,J.P. Vandenbroucke
Low-moleclar-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis
Lancet, 340 (1992), pp. 152-156
A. Leizorovicz,M.C. Haugh,F.R. Chaouis,M.M. Samama,J.P. Boissel
Low molecular weight heparin in prevention of perioperative thrombosis
BrMed J, 340 (1992), pp. 913-920
M. Monreal,E. Lafoz,R. Salvador,J. Roncales,A. Navarro
Adverse effects of three different forms of heparin therapy: thrombocytopenia, increased transaminases, and hyperkalaemia
Eur J Clin Pharmacol, 37 (1989), pp. 415-418
M. Monreal,E. Lafoz,A. Olivé,L. Del Río,C. Vedia
Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin
Thromb Haemost, 71 (1994), pp. 7-11
A. Leizorovicz,G. Simonneau,H. Decousus,J.P. Poissel
Comparison of efficacy and safety of low molecular weight heparins and unfractinated hepar in in initial treatment of deep venous thrombosis: a meta-analysis
Br Med J, 309 (1994), pp. 299-304
A.W.A. Lensing,M.H. Prins,B.L. Davidson,J. Hirsh
Treatment of deep-vein thrombosis with low molecular weight heparin. A metaanalysis
Arch Intern Med, 155 (1995), pp. 601-607
S. Siragusa,B. Cosmi,F. Piovella,J. Hirsh,J.S. Ginsberg
Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta-analysis
G. Meyer,F. Brenot,G. Pacouret,G. Simonneau,K. Gillet Kuvin,B. Charbonnier
Subcutaneous low-molecular-weight heparin Fragmin versus intravenous unfractionated heparin in the treatment of acute non massive pulmonary embolism: an open randomized pilot study
Thromb Haemost, 74 (1995), pp. 1432-1435
H. Decousus,A. Leizorovicz,F. Parent,Y. Page,B. Tardy,P. Girard
A clinical trial of vena cava filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis
N Engl J Med, 338 (1998), pp. 409-415 http://dx.doi.org/10.1056/NEJM199802123380701
L. Falkon,D. Sáenz-Campos,R. Antonijoan,S. Martin,M. Barbanoj,J. Fontcuberta
Bioavailability and pharmacokinetics of a new low-molecular-weight heparin (RO-11)- a three way croos-over study in healthy volunteers
Thromb Res, 78 (1995), pp. 77-86
L. Falkon,M. Gari
Kinetic behaviour of the TFPI and anti-Xa effects, after the injection of a LMWH (RO-11) in healthy subjects
Thromb Haemost, 73 (1995), pp. 728-729
E. Moreno González,J. Fontcuberta,F. De la Llama
Prophylaxis of thromboembolic disease with RO-11 (ROVI), during abdominal surgery.EMRO1 (Grupo Estudio Multicentrico RO-11)
Hepatogastroenterology, 43 (1996), pp. 744-747
L. Falkon,M. Bayes,G. Frontera,M. Gari,M. Barbanoj,J. Fontcuberta
Pharmacokinetics and tolerability of a new low molecular mass heparin(RO-11) in healthy volunteers. A dose-finding study within the therapeutical range
Thromb Haemost, 77 (1997), pp. 133-136
L. Falkon,M. Gari,M. Barbanoj,J. Amiral,J. Fontcuberta
Tissue factor pathway inhibitor and anti-FXa kinetic profiles of a new low-molecular-mass heparin, Bemiparin, at therapeutic subcutaneous doses
Blood Coagul Fibrinolysis, 9 (1998), pp. 137-141
Correspondencia: Servicio de Medicina Interna. Hospital Universitari Germans Trias i Pujol. 08916 Badalona. Barcelona. (Manuel Monreal Bosch mmonreal@ns.hugtip.scs.es)
Copyright © 2000. Elsevier España, S.L.