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FI 2016

© Thomson Reuters, Journal Citation Reports, 2016

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  • Factor de Impacto: 1,125(2016)
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© Thomson Reuters, Journal Citation Reports, 2016

Med Clin 2005;125:766-9 - DOI: 10.1016/S0025-7753(05)72185-0
Proteína C reactiva en la fase aguda del ictus
C-reactive protein in the acute phase of ischemic stroke
José Carlos Arévalo-Lorido??, , Juana Carretero-Gómez, José María Calvo- Romero, Jorge Manuel Romero-Requena, Juan Luis Pérez-Alonso, Concepción Gutiérrez-Montaño, Carmen Ortiz-Descane
Servicio de Medicina Interna. Hospital Comarcal de Zafra. Zafra. Badajoz. España
Recibido 22 marzo 2004, Aceptado 07 junio 2005
Background and objective

We aimed to assess the prognostic importance of C-reactive protein (CRP) in the acute phase of ischemic stroke in-patients.

Patients and method

One hundred and seventeen patients within 48h after index ischemic stroke were included. CRP levels and blood samples were obtained at this time, and a brain computerized tomography or magnetic resonance imaging were performed. Neurological and functional disability were evaluated and patients were divided according to the outcome into the following categories: transient ischemic attack, favorable stroke, and non-favorable stroke.


32 in-patients were classified as transient ischemic attack, 31 as favourable stroke, and 54 as non-favorable stroke. There was a worsening in neurological (p<0.0001) and functional (p<0.005) disabilities from the TIA group to non-favorable stroke. The CRP mean, by category, was 1.7, 1.07 and 3.6mg/dl, respectively (p<0.0001).


We found increased levels of CRP in the non-favorable stroke category, that was related with neurological and functional disabilities, and with radiological findings, mainly when levels were greater than 3.6 (0.49) mg/dl.

Palabras clave
Proteína C reactiva, Accidente cerebrovascular, Enfermedad cerebrovascular
Key words
C-reactive protein, Ischemic accident, Ischemic stroke
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Correspondencia: Dr. J.C. Arévalo-Lorido. Servicio de Medicina Interna. Hospital Comarcal de Zafra. Ctra. Badajoz-Granada, s/n. 06300 Zafra. Badajoz. España. (José Carlos Arévalo-Lorido jocarlor@inicia.es)
Copyright © 2005. Elsevier España S.L.