¿Aún no está registrado?

Cree su cuenta. Regístrese en Elsevier y obtendrá: información relevante, máxima actualización y promociones exclusivas.

Registrarme ahora
Ayuda - - Regístrese - Teléfono 902 888 740
Buscar en

Indexada en:

Index Medicus/MEDLINE, Scopus, IBECS, IME, MEDES


  • SCImago Journal Rank (SJR):0,195
  • Source Normalized Impact per Paper (SNIP):0,103
Clin Invest Arterioscl 2004;16:18-22 - DOI: 10.1016/S0214-9168(04)78950-0
Mejoría de la presión arterial en la obesidad mórbida tras dieta de muy bajo contenido calórico
E. Solá Izquierdo1, , C. Morillas Ariño, S. Garzón Pastor, R. Royo Taberner, S. García Torres, A. Hernández Mijares
Sección de Endocrinología. Hospital Universitario Doctor Peset. Valencia. España

To analyze the presence of blood pressure disorders in patients with morbid obesity and the influence of weight loss achieved by diet on these disorders. To evaluate the influence of gender on the presence of blood pressure disorders and on the response to diet.


All patients with morbid obesity (23 men and 36 women) underwent anthropometric evaluation. Blood pressure (systolic and diastolic arterial, mean and pulse pressure) was evaluated before and after an intervention that alternated very-low caloric diets with conventional low caloric diets. The results before and after the intervention were compared using Student’s t-test for paired samples (after confirming that the conditions for its application were fulfilled).


The presence of blood pressure disorders was high in patients with morbid obesity. Marked weight loss was achieved with diet, especially in men (95% confidence interval: 26.9 to 39.8 kg in men, and 13.5 to 20.3 kg in women). The presence of blood pressure disorders was considerably reduced after weight loss, with a significant decrease in systolic blood pressure in both sexes (95% confidence interval: men 4.1 to 28.1 mmHg, women 1 to 13.7 mmHg) and in diastolic blood pressure in women (95% confidence interval: 0.4 to 30.5 mmHg).


Patients with morbid obesity show a high prevalence of blood pressure disorders. A significant reduction in this prevalence was achieved with diet over one year.

Palabras clave
Obesidad mórbida, Dieta, Hipertensión arterial
El Texto completo solo está disponible en PDF
W.B. Kannel,R.B. D’Agostino,J. Cobb
Effect of weight on cardiovascular disease
Am J Clin Nutr, 63 (1996), pp. 445S-447S
J. Stevens,J. Cai,E.R. Pamur,D.F. Williamson,M.J. Thun,J.L. Wood
The effect of age on the association between body-mass index and mortality
W.B. Kannel,N. Brand,J.J.J. Skinner,T.W. Dawber,P.M. McNamara
The relation of adiposity to blood pressure and development of hypertension. The Framingham Study
Ann Intern Med, 67 (1967), pp. 48-59
T.B. Van Itallie
Health implications of overweight and obesity in the United States
Ann Intern Med, 103 (1985), pp. 983-988
J.A. Kanaley,M.L. Andresen-Reid,L.V. Oenning,B.A. Kottke,M.D. Jensen
Differential health benefits of weight loss in upper-body and lower-body obese women
Am J Clin Nutr, 57 (1993), pp. 20-26
E. Solá,C. Morillas,S. Garzón,R. Royo,A. Núñez,D. Bautista
Factores de riesgo cardiovascular en pacientes con obesidad mór- bida: influencia de la pérdida de peso
Med Clin (Barc), 119 (2002), pp. 485-488
J.B. Dixon,P.E. O’Brien
Changes in comorbidities and improvements in quality of life after LAP-BAND placement
Am J Surg, 184 (2002), pp. S51-S54
National Task Force on the Prevention and Treatment of Obesity
Jama, 270 (1993), pp. 967-974
W. Ricart,F. González-Huix,V. Conde
Evaluation of the nutritional status through determination of anthropometric parameters: new charts for the working population of Catalonia. Group for the Evaluation of body composition in the population of Catalonia
Med Clin (Barc), 100 (1993), pp. 681-691
Joint National Committee on detention evaluation, and treatment of high blood pressure. The sixth report of Joint National Committee
Arch Intern Med, 157 (1997), pp. 2413-2446
Dirección General de Planificación Sanitaria. Consenso para el control de la hipertensión arterial en España
S. Toubro,A. Astrup
Randomised comparison of diets for maintaining obese subjects weight after major weight loss: ad lib, low fat, high carbohydrate diet vs fixed energy intake
Bmj, 314 (1997), pp. 29-34
C. Walton,B. Less,D. Crook,M. Worthington,I.F. Godsland,J.C. Stevenson
Body fat distribution, rather than overall adiposity, influences serum lipids and lipoproteins in healthy men independently of age
Am J Med, 99 (1995), pp. 459-464
E. Ferrannini
Physiological and metabolic consequences of obesity
Metabolism, 44 (1995), pp. 15-17
K. Osei
Insulin resistance and systemic hypertension
Am J Cardiol, 84 (1999), pp. 33-36
M.T. Velasquez,R.G. Hoffmann
Overweight and obesity in hypertension
Q J Med New Series, 54 (1985), pp. 205-212
D.E. Schotte,A.J. Stunkard
The effects of weight reduction on blood pressure in 301 obese patients
Arch Intern Med, 150 (1990), pp. 1701-1704
H.E. Eliahou,A. Iaina,T. Gaon,J. Shochat,M. Modan
Body weight reduction necessary to attain normotension in the overweight hypertensive patient
Int J Obes, 5 (1981), pp. 157-163
H.E. Eliahou,J. Laufer,A. Blau
Effect of low-calorie diets on the sympathetic nervous system, body weight, and plasma insulin in overweight hypertension
Am J Clin Nutr, 56 (1992), pp. 175S-178S
Correspondencia: Eva Solá Izquierdo. Hospital Universitario Doctor Peset. Avda. Gaspar Aguilar, 90. 46017 Valencia. España.
Copyright © 2004. Sociedad Espa??ola de Arteriosclerosis y Elsevier Espa??a, S.L.