Severe necrotising pneumonia in a fully immunised infant: A case of serotype 3 pneumococcal conjugate vaccine failure

Oligbu, G.; Ahmed, L.; Chia, G.

doi:10.1016/j.vacune.2018.09.002

ISSN: 2445-1460

Official journal of the Asociación Española de Vacunología (AEV) Vacunas is a peer-reviewed journal supported by an advisory board of experts in the field of vaccinology. The aim of the journal is to contribute to the dissemination of the scientific advances made in the area of basic and applied research in the field of vaccine-preventable diseases in humans. It places special emphasis on aspects associated with planning and evaluation (epidemiology of vaccine-preventable diseases, development of vaccination programs, evaluation of the efficacy, effectiveness and efficiency of vaccinations). Vacunas publishes, in Spanish and in English, Editorials, Original Articles, Special Articles, Reviews, Strategies and Vaccination Programs. There are also sections on Literature Reviews, News and on Congresses associated with vaccinations. The peer review process is done anonymously by reviewers with expertise in the area of knowledge of each manuscript as well as experts in methodology or statistics, as determined by the Editorial board, which works towards maintaining an efficient editorial process in order for the manuscripts to be published as soon as possible.

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Vol. 19. Issue 2.

Pages 99-102 (July - December 2018)

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Vol. 19. Issue 2.

Pages 99-102 (July - December 2018)

Case report

DOI: 10.1016/j.vacune.2018.09.002

Severe necrotising pneumonia in a fully immunised infant: A case of serotype 3 pneumococcal conjugate vaccine failure

Neumonía necrotizante grave en un lactante completamente inmunizado: un caso de fracaso de la vacuna conjugada neumocócica serotipo 3

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G. Oligbua,b,

Corresponding author

godwin.oligbu@nhs.net

Corresponding author.

, L. Ahmeda, G. Chiaa

a London Northwest Healthcare Trust, London, UK

b Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St. George's, University of London, UK

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Abstract

We describe a case of severe necrotising pneumonia in a fully immunised infant due to serotype 3 vaccine failure. A full immunological work up was unremarkable, and the child recovered fully with no residual complications.

Keywords:

Streptococcus pneumonia

Pneumococcal conjugate vaccine

Necrotising pneumonia

Vaccine failure

Resumen

Describimos un caso de neumonía necrosante grave en una fallo de la vacuna contra el serotipo 3 de un lactante completamente inmunizado. El trabajo inmunológico completo fue normal y el niño se recuperó completamente sin complicaciones residuales.

Palabras clave:

Neumonía estreptocócica

Vacuna conjugada neumocócica

Neumonía necrotizante

Falla de la vacuna

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