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Vol. 50. Issue 1.
Pages 3-7 (January - March 2017)
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Vol. 50. Issue 1.
Pages 3-7 (January - March 2017)
Original Article
The spectrum of glomerular disease between the years 2003 and 2015 in Columbia: A review of 12,613 cases
El espectro de enfermedades glomerulares entre los años 2003 y 2015 en Colombia: una revisión de 12.613 casos
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Luis Eduardo Barrera-Herreraa, Rocío del Pilar López Panquevaa,b, Adriana Alejandra Flórez Vargasa,b, Rafael Enrique Andrade Péreza,b,c,
Corresponding author
rafaandrade@hotmail.com

Corresponding author.
a Department of Pathology and Laboratories, University Hospital Fundación Santa Fe de Bogotá, Bogotá, Colombia
b School of Medicine, Universidad de los Andes, Bogotá, Colombia
c School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia
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Tables (4)
Table 1. Proposed list of glomerular diseases.
Table 2. Frequency of glomerulopathies in males and females.
Table 3. Biopsy-proven primary glomerulopathies between the years 2003 and 2015.
Table 4. Prevalence of biopsy-proven primary glomerulopathies in adults and children previously reported.
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Abstract
Background

The prevalence of glomerular disease (GD) varies according to the different socio-demographic characteristics of each population. For the first time we present the prevalence of the different forms of GD among patients from several different areas of Columbia.

Methods

Data from 12,613 renal biopsies studied at our University Hospital between 2003 and 2015 was reviewed. Pathology results were classified according to a list of renal diseases proposed by various authors.

Results

Focal segmental glomerulosclerosis was present in 22%, IgA disease in 21%, Lupus nephritis in 17%, membranous glomerulonephritis in 13% and thin basal membrane disease in 9%.

Conclusions

This study confirms that focal segmental glomerulosclerosis and IgA disease are the most prevalent GDs found in Columbian patients. This is the first study to analyze GDs in a Columbian population and we recommend that a national registry system be created to collect comprehensive information from future research.

Keywords:
Epidemiology
Glomerulonephritis
Renal biopsy
Renal pathology
Renal biopsy registry
Resumen
Antecedentes

La prevalencia de las enfermedades glomerulares varía según las características sociodemográficas de cada población. Por primera vez presentamos la prevalencia de las diferentes formas de enfermedad glomerular (EG) entre pacientes de varias regiones de Colombia.

Método

Se revisaron los datos de 12.613 biopsias renales estudiadas en nuestro hospital universitario entre los años 2003 y 2015. Se clasificaron los resultados anatomopatológicos según una lista de enfermedades renales propuesta por varios autores.

Resultados

Se encontró glomeruloesclerosis focal y segmentaria en el 22%, enfermedad IgA en el 21%, nefritis lupoide en el 17%, glomerulonefritis membranosa en el 13% y enfermedad de la membrana basal delgada en el 9%.

Conclusiones

Nuestro estudio confirma que la glomeruloesclerosis focal y segmentaria y la enfermedad IgA son los más prevalentes entre pacientes colombianos. Esto es el primer estudio que ha analizado EG en la población colombiana, y recomendamos la creación de un registro nacional para recopilar y completar información de investigaciones futuras.

Palabras clave:
Epidemiología
Glomerulonefritis
Biopsia renal
Patología renal
Registro

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