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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tu...
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Vol. 36. Issue 2.
Pages 103-109 (March - April 2017)
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Vol. 36. Issue 2.
Pages 103-109 (March - April 2017)
Special collaboration
Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas
Valor adicional de la imagen híbrida con SPECT/TC en tumores neuroendocrinos, tumores adrenales, feocromocitomas y paragangliomas
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K.K. Wonga,b, S. Chondrogiannisc, D. Fusterd, C. Ruizd, M.C. Marzolac, F. Giammarilee, P.M. Collettif, D. Rubelloc,
Corresponding author
a Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, MI, USA
b Nuclear Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
c Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Molecular Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy
d Department of Nuclear Medicine, Hospital Clínic, Barcelona, Spain
e Nuclear Medicine Department, University of Lyon, Lyon, France
f Department of Nuclear Medicine, University of Southern California, Los Angeles, CA, USA
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Abstract

The aim of this review was to evaluate the potential advantages of SPECT/CT hybrid imaging in the management of neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas. From the collected data, the superiority of fused images was observed as providing both functional/molecular and morphological imaging compared to planar imaging. This provided an improvement in diagnostic imaging, with significant advantages as regards: (1) precise locating of the lesions; (2) an improvement in characterization of the findings, resulting higher specificity, improved sensitivity, and overall greater accuracy, (3) additional anatomical information derived from the CT component; (4) CT-based attenuation correction and potential for volumetric dosimetry calculations, and (5) improvement on the impact on patient management (e.g. in better defining treatment plans, in shortening surgical operating times). It can be concluded that SPECT/CT hybrid imaging provides the nuclear medicine physician with a powerful imaging modality in comparison to planar imaging, providing essential information about the location of lesions, and high quality homogeneous images.

Keywords:
SPECT/CT
Hybrid systems
Neuroendocrine tumors
Adrenal tumors
Pheochromocytoma
Paraganglioma
Resumen

El objetivo de esta revisión es evaluar las ventajas que puede ofrecer la imagen híbrida mediante SPECT/TC en el manejo de los tumores neuroendocrinos, tumores adrenales, feocromocitomas y paragangliomas. A partir de los datos recogidos de la literatura se pone de manifiesto la superioridad de las imágenes de fusión que proporcionan información morfológica y funcional/molecular con respecto a la imagen planar, permitiendo una mejora diagnóstica con importantes ventajas: 1) localización precisa de las lesiones; 2) mejora en la caracterización de los hallazgos, lo que supone una mayor especificidad y sensibilidad y por lo tanto una mayor exactitud diagnóstica; 3) información anatómica adicional obtenida con la TC; 4) corrección de la atenuación que permite realizar cálculos dosimétricos volumétricos basados en la TC; 5) mejora en el impacto del manejo del paciente como afinar el tipo de tratamiento o la reducción del tiempo quirúrgico. En resumen, la SPECT/TC es una herramienta importante para el manejo de este tipo de tumores ya que en comparación con la imagen planar da información esencial sobre la localización y la caracterización de las lesiones.

Palabras clave:
SPECT/TC
Imagen híbrida
Tumores neuroendocrinos
Tumores adrenales
Feocromocitoma
Paraganglioma

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