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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) 18F-FDG PET/CT in locally advanced cervical cancer: A review
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Vol. 38. Issue 1.
Pages 59-68 (January - February 2019)
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Vol. 38. Issue 1.
Pages 59-68 (January - February 2019)
Continuing Education
18F-FDG PET/CT in locally advanced cervical cancer: A review
PET/TC con 18F-FDG en cáncer de cérvix localmente avanzado
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A.P. Caresia-Arózteguia,
Corresponding author
paulacaresia@gmail.com

Corresponding author.
, R.C. Delgado-Boltonb, S. Alvarez-Ruizc, M. del Puig Cózar-Santiagod, J. Orcajo-Rincone, M. de Arcocha-Torresf, M.J. García-Vellosog, on behalf of the Grupo de Trabajo de Oncología de la Sociedad Española de Medicina Nuclear e Imagen Molecular
a Servicio de Medicina Nuclear, UDIAT, Hospital de Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain
b Departamento de Diagnóstico por Imagen y Medicina Nuclear, Hospital San Pedro-Centro de Investigación Biomédica de La Rioja (CIBIR), Logroño, Spain
c Servicio de Medicina Nuclear, Hospital Universitario Miguel Servet, Zaragoza, Spain
d Servicio de Medicina Nuclear, ERESA, Hospital General Universitario de Valencia, Valencia, Spain
e Servicio de Medicina Nuclear, Hospital General Universitario Gregorio Marañón, Madrid, Spain
f Unidad de Radiofarmacia, Hospital Universitario Marqués de Valdecilla, Santander, Spain
g Servicio de Medicina Nuclear, Clínica Universidad de Navarra, Pamplona, Spain
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Figures (1)
Tables (5)
Table 1. Classification of cervical cancer according to FIGO and the equivalent TNM.2,3
Table 2. Rate of survival by stages according to the AJCC. Statistics based on information collected by the National Database on cancer from 2000 and 2002. These survival statistics are available for the 2010 classification system.4,5
Table 3. Presurgical factors of bad prognosis in cervical cancer.
Table 4. Diagnostic procedures recocmmended by the different scientific socieites.
Table 5. List of metaanalyses of cervical cancer with the diagnostic yield of PET or PET/CT, CT, and MR in the evaluation of lymph node involvement.
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Abstract

Cervical cancer is the second most common gynecological cancer worldwide. In locally advanced cervical cancer, 18F-FDG PET/CT has become important in the initial staging, particularly in the detection of nodal and distant metastasis, aspects with treatment implications and prognostic value.

The aims of this study were to review the role of 18F-FDG PET/CT in uterine cervical cancer, according to the guidelines of the main scientific institutions (FIGO, NCCN, SEGO, SEOM, ESGO, and ESMO) and its diagnostic accuracy compared to conventional radiological techniques, as well as to review the acquisition protocol and its utility in radiotherapy planning, response assessment and detection of recurrence.

Keywords:
Cervical cancer
18F-FDG PET/CT
Staging
Radiotherapy planning
Response
Recurrence
Resumen

El cáncer de cérvix es el segundo cáncer ginecológico en frecuencia a nivel mundial. En tumores localmente avanzados la PET/TC con 18F-FDG tiene un papel relevante en la detección de enfermedad ganglionar y a distancia, factores en los que se basan el tratamiento y el pronóstico de estas pacientes.

El objetivo de este trabajo es revisar las indicaciones actuales de la PET/TC con 18F-FDG en el cáncer de cérvix para cada una de las principales sociedades científicas (FIGO, NCCN, SEGO, SEOM, ESGO, ESMO) y la rentabilidad diagnóstica de la prueba comparada con las técnicas radiológicas convencionales, así como el procedimiento y su utilidad en la planificación de la radioterapia, en la valoración de respuesta y en la detección de recidiva.

Palabras clave:
Cáncer de cérvix
PET/TC con 18F-FDG
Estadificación
Planificación de radioterapia
Respuesta
Recidiva

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