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Case report
Rhupus syndrome. A rare combination
Síndrome de Rhupus. Una superposición infrecuente
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Urbano Solis Cartasa,b,
Corresponding author
umsmwork74@gmail.com

Corresponding author.
, José Pedro Martínez Larrartec, Dinorah Marisabel Prada Hernándezd, Jorge Alexis Gómez Morejónd, Jorge Luis Valdés Gonzálezb, Claudino Molinero Rodríguezd
a Facultad de Ciencias de la Salud, Universidad Nacional de Chimborazo, Riobamba, Chimborazo, Ecuador
b Facultad de Salud Pública, Escuela Superior Politécnica Chimborazo, Riobamba, Chimborazo, Ecuador
c Facultad de Medicina Dr. Miguel Enríquez, Laboratorio Central de Líquido Cefalorraquídeo (LABCEL), Universidad de Ciencias Médicas, La Habana, Cuba
d Centro Nacional de Reumatología, Universidad de Ciencias Médicas, La Habana, Cuba
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Received 19 May 2016. Accepted 08 May 2017
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Abstract

Rhupus syndrome is a rare combination of rheumatoid arthritis and systemic lupus erythematosus, and is characterized by the presence of erosive arthritis together with symptoms and signs of systemic lupus erythematosus. Among its complications, is the presence of rheumatoid nodules, and neurological and renal involvement that further complicates its prognosis, thus significantly reducing the perception of health-related quality of life in patients who suffer from it. The case is presented of a female patient diagnosed with lupus erythematosus, who during the course of the disease, developed clinical and humoral signs that led to the diagnosis of syndrome Rhupus syndrome. This is believed to of relevance to the knowledge of the medical community.

Keywords:
Rheumatoid arthritis
Systemic lupus erythematosus
Rhupus syndrome
Resumen

El síndrome de Rhupus es una rara superposición de artritis reumatoide y lupus eritematoso sistémico, que se caracteriza por la presencia de una poliartritis erosiva asociada a síntomas y signos de lupus eritematoso sistémico. Entre sus complicaciones destaca la presencia de nódulos reumatoideos, afectación neurológica y renal que complican más aún la evolución del caso, disminuyendo considerablemente la percepción de la calidad de vida relacionada con la salud de los pacientes que lo padecen. Se presenta el caso de una paciente mujer con diagnóstico de lupus eritematoso, que desarrolla en el curso de la enfermedad manifestaciones clínicas y humorales que permiten llegar al diagnóstico de un síndrome de Rhupus, lo cual consideramos sea de importancia para el conocimiento de la comunidad médica.

Palabras clave:
Artritis reumatoide
Lupus eritematoso sistémico
Síndrome de Rhupus

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