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Positron emission tomography/CT scanning in the diagnosis of neurosarcoidosis – A case in point.
Utilidad de la tomografía por emisión de positrones - tomografía computada para el diagnóstico de neurosarcoidosis. A propósito de un caso
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Leonardo Bohórquez, Diana Carolina Vargas
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diacavan@gmail.com

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Departamento Medicina Interna, Clínica Partenón, Bogotá, Colombia
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Received 24 January 2017. Accepted 14 July 2017
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Table 1. Patient's laboratory findings (blood and cerebrospinal fluid).
Abstract

The diagnosis of neurosarcoidosis is difficult because of its clinical and radiological polymorphism. Any part of the central nervous system may be affected, and imaging studies are usually inconclusive. The case is presented of a young patient with headache, bilateral facial paralysis, and subacute lymphocytic meningitis in whom, despite biochemical and imaging studies the origin was not identified. Using 18-PET-FDG helped to identify a hypermetabolic mediastinal adenopathy, with pathology reporting non-caseating granulomas, findings suggestive of sarcoidosis. This reflects its usefulness for the diagnosis and staging of the disease, especially in situations where there is no evidence from other imaging studies of extra-neural disease.

Keywords:
Sarcoidosis
Neurosarcoidosis
Facial palsy
Headache
Meningitis
Positron emission tomography
Resumen

El diagnóstico de la neurosarcoidosis es difícil por su polimorfismo clínico y radiológico, y cualquier parte del sistema nervioso central puede estar afectado. Presentamos el caso de una paciente joven con cefalea, meningitis linfocitaria subaguda, en quien a pesar de estudios bioquímicos e imagenológicos no se identificó la etiología. La tomografía por emisión de positrones con 18 fluorodeoxiglucosa permitió la identificación de un ganglio mediastinal hipermetabólico, con informe de patología de granulomas no caseificantes, hallazgos sugestivos de sarcoidosis, reflejando la utilidad de la tomografía por emisión de positrones con 18 fluorodeoxiglucosa para el diagnóstico y estadificación de la enfermedad, especialmente en las situaciones en las que no hay evidencia mediante otros estudios imagenológicos de enfermedad extraneural.

Palabras clave:
Sarcoidosis
Neurosarcoidosis
Diplejía facial
Cefalea
Meningitis
Tomografía por emisión de positrones

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