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Original Investigation
Depression in Rheumatoid Arthritis
Depresión en artritis reumatoide
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Génessis Maldonadoa,
Corresponding author
, Carlos Ríosb, Carlos Paredesa, Christian Ferroc, María José Intriagoa, Claudia Aguirrea, Víctor Avilaa, Mario Morenod
a Facultad de Medicina, Universidad de Especialidades Espíritu Santo, Guayaquil, Ecuador
b Centro de Reumatología y Rehabilitación, Guayaquil, Ecuador
c Facultad de Medicina, Universidad Católica Santiago de Guayaquil, Guayaquil, Ecuador
d Servicio de Reumatología, Hospital Luis Vernaza, Guayaquil, Ecuador
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Received 04 October 2016. Accepted 09 December 2016
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Table 1. Comorbidities in patients with RA.
Abstract
Introduction

Depression is significant comorbidity in patients with rheumatoid arthritis (RA), with many factors, such as disease activity, pain, and disability determining its development.

Materials and method

A cross-sectional study including patients with rheumatoid arthritis was conducted to determine prevalence of depression using the Patient Health Questionnaire (PHQ-9), and its relationship with disease activity using DAS-28. The HAQ-DI was used to determine functional disability and the number of painful and swollen joints.

Results

Depression was observed in 42.9% of the patients. An association was found between depression, DAS-28 and HAQ-DI. It was also found that 70% of the patients with high activity disease and 38% of the patients with functional disability had moderate-severe depression. The number of painful and swollen joints was greater in patients with severe depression than in patients with mild depression. Patients with greater depression referred to more intense pain according to the visual analog pain scale.

Keywords:
Rheumatoid arthritis
Depression
Epidemiology
Patient Health Questionnaire 9
Resumen
Introducción

La depresión es una importante comorbilidad en pacientes con artritis reumatoide; diversos factores como la actividad de la enfermedad, el dolor y la discapacidad contribuyen a su desarrollo.

Materiales y métodos

Se realizó un estudio transversal en pacientes con artritis reumatoide para determinar la prevalencia de depresión, utilizando el cuestionario Patient health questionnaire (PHQ-9) y su relación con la actividad de la enfermedad mediante DAS-28 y la discapacidad funcional mediante HAQ-DI.

Resultados

El 42.9% de los pacientes presentaron depresión. Se encontró una asociación entre depresión con DAS-28 y HAQ-DI, ya que el 70% de los pacientes con alta actividad de la enfermedad y el 38% de los pacientes con discapacidad funcional presentaron depresión de moderada a grave. El número de articulaciones dolorosas y tumefactas fue mayor en los pacientes con depresión grave que en aquellos con depresión leve. Los pacientes con mayor depresión referían un dolor más intenso según la escala visual del dolor.

Palabras clave:
Artritis reumatoide
Depresión
Epidemiología
Patient health questionnaire 9

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