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Vol. 4. Issue 1.
Pages 52-58 (April 2017)
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Vol. 4. Issue 1.
Pages 52-58 (April 2017)
Revisión
Efectos del bisfenol A en la reproducción femenina
Effects of bisphenol A on female reproduction
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21
Shuyana Deba, Paula Núñez
Corresponding author
nunezpaula@uniovi.es

Autor para correspondencia.
Área de Fisiología, Departamento de Biología Funcional, Facultad de Medicina y Ciencias de la Salud, Universidad de Oviedo, Oviedo, España
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Resumen

El bisfenol A es un disruptor endocrino, es decir, una sustancia química capaz de alterar el sistema hormonal, que se utiliza como monómero o aditivo en la industria del plástico. La población está expuesta de forma crónica a esta sustancia con función estrogénica, cuya concentración en muestras humanas es en muchas ocasiones más elevada que la concentración necesaria para conseguir respuestas positivas en ensayos estrogénicos in vitro, lo que podría tener efectos adversos en la salud reproductiva de la mujer. En esta revisión se resumen diversos experimentos que demuestran cómo la exposición al bisfenol A durante el desarrollo fetal y/o la edad adulta altera y perjudica la fertilidad femenina.

Palabras clave:
Bisfenol A
Reproducción
Fertilidad
Hembras
Abstract

Bisphenol A is an endocrine disruptor, namely a chemical substance able to alter the hormonal system, as well as being a chemical that is used as a monomer or additive in the plastic industry. The population is continually being exposed to this endocrine disruptor substance with oestrogenic function. Its levels in human samples are often higher than the concentrations required to obtain positive oestrogenic responses in in vitro tests, which could have adverse effects on female reproductive medicine. In fact, this review summarises the studies that show how bisphenol A induces alterations and damages during foetal development and female fertility in adulthood.

Keywords:
Bisphenol A
Reproduction
Fertility
Female

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