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Vol. 148. Issue 8.
Pages 351-353 (April 2017)
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Vol. 148. Issue 8.
Pages 351-353 (April 2017)
Brief report
Prevalence of hypertension and other cardiovascular risk factors in subjects with subclinical hypothyroidism
Prevalencia de hipertensión arterial y otros factores de riesgo cardiovascular en la población con hipotiroidismo subclínico
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Lidia Gonzalez Gila, Alejandro de la Sierrab,
Corresponding author
a Centro Atención Primaria CAP Rambla de Terrassa, Mutua Terrassa, Barcelona, Spain
b Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Barcelona, Spain
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Table 1. Comparison of demographics, risk factors, blood pressure and laboratory values between cases and controls.
Abstract
Background and objective

To assess the prevalence of hypertension, diabetes, and dyslipidaemia in subjects with subclinical hypothyroidism (SH) in comparison with an age- and sex-matched control group.

Patients and methods

Case-control study with 240 subjects with SH and 480 controls carried out on patients aged 35–75 years admitted to a Primary Care Centre. The prevalence of hypertension, diabetes and dyslipidaemia, as well as blood pressure, plasma glucose, and lipid profiles, were evaluated in both groups.

Results

No differences were observed neither in the prevalence of hypertension (34.2% vs. 29.6%) or diabetes (12.1% vs. 10%) nor in mean values of blood pressure or plasma fasting glucose. Subjects with SH had an increased prevalence of lipid abnormalities (72.1% vs. 57.7%; p<0.001), and increased mean values of total cholesterol (205±34 vs. 193±35mg/dL; p<0.001), compared to the control group.

Conclusion

Patients with SH have an increased prevalence of lipid abnormalities. This can be responsible for an increased cardiovascular risk in such patients.

Keywords:
Subclinical hypothyroidism
Arterial hypertension
Dyslipidaemia
Resumen
Fundamento y objetivo

Determinar la prevalencia de hipertensión arterial, así como de diabetes y dislipidemia en el hipotiroidismo subclínico (HS), comparado con un grupo control de la misma edad y sexo.

Pacientes y método

Estudio de casos (HS) (N=240) y controles (N=480) realizado en un Centro de Atención Primaria en individuos entre 35 y 75 años. Se evaluó la presencia de hipertensión arterial, diabetes y dislipidemia, así como las cifras de presión arterial, perfil lipídico y glucemia en ayunas.

Resultados

No se observaron diferencias entre casos y controles en la prevalencia de hipertensión arterial (34,2 vs. 29,6%) o de diabetes (12,1 vs. 10%), ni en los valores de presión arterial o de glucemia en ayunas. Los pacientes con HS presentaron con mayor frecuencia dislipidemia (72,1 vs. 57,7%; p<0,001) así como cifras más elevadas de colesterol total (205±34 vs. 193±35mg/dl; p<0,001), con respecto a los controles.

Conclusiones

Los pacientes con HS presentan una prevalencia elevada de trastornos lipídicos, sin diferencias significativas en hipertensión arterial o diabetes. Ello muestra la presencia de un riesgo cardiovascular incrementado en dicha población.

Palabras clave:
Hipotiroidismo subclínico
Hipertensión arterial
Dislipidemia

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