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Endocrinol Nutr 2005;52:297-308 - DOI: 10.1016/S1575-0922(05)74800-2
Inhibidores de la absorción del colesterol
Cholesterol absorption inhibitors
E. Boix??, , A.M. Picó
Sección de Endocrinología y Nutrición. Hospital General Universitario de Alicante. Alicante. España
Received 29 July 2004, Accepted 14 March 2005

Hypercholesterolemia is a cardiovascular risk factor. Effective and long-term reduction of total and low-density lipoprotein cholesterol concentrations lowers mortality from coronary heart disease. Until now the most effective cholesterol-lowering drugs have been hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins). However many patients do not achieve standard treatment goals as defined by clinical guidelines with statins in monotherapy and require combination therapy with other lipid lowering drugs. The present review discusses the pharmacologic agents that act through inhibition of cholesterol absorption and their role in the clinical management of hypercholesterolemia.

Palabras clave
Colesterol, Absorción intestinal, Ezetimiba
Key words
Cholesterol, Intestinal absorption, Ezitimibe
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Correspondencia: Dra. E. Boix Carreño. Partida de Alzabares Alto. Polígono 1. 146-147-A. 03290 Elche. Alicante. España. (E. Boix ev.boixc@coma.es)
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