Buscar en
Ciência & Tecnologia dos Materiais
Toda la web
Inicio Ciência & Tecnologia dos Materiais Bioactive microsphere-based coating for biomedical-textiles with encapsulated an...
Journal Information
Vol. 26. Issue 2.
Pages 118-125 (July - December 2014)
Share
Share
Download PDF
More article options
Vol. 26. Issue 2.
Pages 118-125 (July - December 2014)
Full text access
Bioactive microsphere-based coating for biomedical-textiles with encapsulated antimicrobial peptides (AMPs)
Visits
1962
Laura Antunes, Graça Faustino, Claúdia Mouro, Joana Vaz, Isabel C. Gouveia
Corresponding author
igouveia@ubi.pt

Corresponding author.
FibEnTech – Fiber Materials and Environmental Technologies Research Center, University of Beira Interior, 6201-001Covilhã, Portugal
This item has received
Article information
Abstract

In this study a sonochemical method was used to prepare chitosan-based-micro/nanoparticle with incorporated antimicrobial- peptides as a novel antimicrobial coating for cotton-gauzes. Characterization in terms of size, morphology and stability was evaluated and microspheres were approximately 2μm in-size and were further coated by the layer-by-layer deposition of alginate (Alg) and chitosan (CS). In addition, an antimicrobial-peptide Dermicidin-1-L was incorporated into the microspheres (CS/AMP microspheres) to give more effective antimicrobial activity against a wider range of microorganisms. Results showed a much higher antimicrobial activity of the CS/AMP-microsphere-coated-cotton in comparison with LbL-Alg/CS-microsphere-coating, without cytotoxicity.

Keywords:
antimicrobial peptides
antimicrobial textiles
medical textiles
microspheres.
Full text is only aviable in PDF
References
[1]
Y. Gao, R. Cranston.
Textile Research Journal., 78 (2008), pp. 60-72
[2]
T. Ristić, L.F. Zemljič, M. Novak, M.K. Kunčič, S. Sonjak, N.G. Cimerman, S. Strnad.
[3]
R. Silva, H. Ferreira, T. Matamá, A.C. Gomes, A. Cavaco-Paulo.
Biotechnology Journal, 7 (2012), pp. 1376-1385
[4]
U. Shimanovih, A. Cavaco-Paulo, Y. Nitzan, A. Gedanken.
Chemistry, 18 (2012), pp. 365-369
[5]
I.C. Gouveia.
Polymers for Advanced Technologies., 23 (2012), pp. 350-356
[6]
K.S. Suslick, M.W. Grinstaff, K.J. Kolberck, M. Wong.
Ultrasonics Sonochemistry, 1 (1994), pp. 65-68
[7]
O. Grinberg, M. Hayun, B. Sredni, A. Gedanken.
Ultrasonics Sonochemistry, 14 (2007), pp. 661-666
[8]
C. Little, M. El-Sharif, M.J. Hepher.
Ultrasonics Sonochemistry, 14 (2007), pp. 375-379
[9]
A.P.R. Johnston, C. Cortez, A.S. Angelatos, F. Caruso.
Current Opinion in Colloid & Interface Science., 11 (2006), pp. 203-209
[10]
Y. Shao, B. Zhu, J. Li, X. Liu, X. Tan, X. Yang.
Materials Science and Engineering.
, C 29 (2009), pp. 936-941
[11]
J. Liu, Y. Zhang, C. Wang, R. Xu, Z. Chen, N. Gu.
The Journal of Physical Chemistry.
, C 114 (2010), pp. 7673-7679
[12]
M. Joshi, S.W. Ali, R. Purwar.
Indian Journal of Fiber Textile Research., 34 (2009), pp. 295-304
[13]
L. Bay, L. Zhu, S. Min, L. Liu, Y. Cai, J. Yao.
Applied Surface Science., 254 (2008), pp. 2988-2995
[14]
M. Bagheri, M. Beyermann, M. Dathe.
Antimicrobial Agents and Chemotherapy., 53 (2009), pp. 1132-1141
[15]
M.F. Zampa, I.M.S. Araujo, V. Costa, C.H.N. Costa, J.R. Santos Jr., V. Zucolotto, C. Eiras, J.R.S.A. Leite.
Nanomedicine: Nanotechnology.
Biology and Medicine., 5 (2009), pp. 352-358
[16]
Y.H. Kim, C.W. Nam, J.W. Choi, J.J. Jang.
Applied Polymer Science., 88 (2003), pp. 1567
[17]
A. Cottell, S.P. Denyer, G.W. Hanlon, D. Ochs, J.-Y. Millard.
Journal of Hospital Infection., 72 (2009), pp. 71
[18]
S.A. Agnihotri, N.N. Mallikarjuna, T.M. Aminabhavi.
Journal of Controlled Release., 100 (2004), pp. 5-28
[19]
Y.L. Xie, M.J. Wang, S.J. Yao.
Langmuir, 25 (2009), pp. 8999-9005
[20]
N. Mei, L. Xuguang, D. Jinming, J. Husheng, W. Liqiao, X. Bingshe.
Carbohydrate Polymers, 78 (2009), pp. 54-59
[21]
G. Genç, G. Narin, O. Bayraktar.
Archives of Materials Science., 29 (2008), pp. 16-28
[22]
A.S. Pedro, E. Cabral-Albuquerque, D. Ferreira, B. Sarmento.
Carbohydrate Polymers, 76 (2009), pp. 501-508
[23]
S. Avivi, A. Gedanken.
Journal Biochemical, 366 (2002), pp. 705-707
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos