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Allergologia et Immunopathologia
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Inicio Allergologia et Immunopathologia Mediterranean diet and childhood asthma
Journal Information
Vol. 44. Num. 2.March - April 2016
Pages 97-188
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Vol. 44. Num. 2.March - April 2016
Pages 97-188
Original Article
DOI: 10.1016/j.aller.2015.04.007
Mediterranean diet and childhood asthma
F.M. Calatayud-Sáeza,
Corresponding author

Corresponding author.
, B. Calatayud Moscoso del Pradoa, J.G. Gallego Fernández-Pachecob, C. González-Martínc, L.F. Alguacil Merinoc,d
a Clínica “La Palma”, Ciudad Real, Spain
b Centro de Salud de Atención Primaria # 1, Ciudad Real, Spain
c Unidad de Investigación Traslacional, Hospital General Universitario, Ciudad Real, Spain
d Universidad San Pablo CEU, Madrid, Spain
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Figures (1)
Tables (5)
Table 1. Characteristics of the sample.
Table 2. Evolution of drug treatments.
Table 3. Questionnaire answers from parents or guardians about improvements in bronchial hyperreactivity. (3) A lot; (2) considerably; (1), a bit; (0) nothing.
Table 4. Anthropometric assessments.
Table 5. KIDMED test (percentage).
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The incidence of bronchial hyperreactivity has increased to one-third of the population in developed countries, which requires the adoption of preventive and therapeutic measures. The objective of the present study was to assess the effects of a traditional Mediterranean diet on patients diagnosed with childhood asthma and determine if there is a beneficial effect from this dietary intervention.


Prospective before–after comparison study of 50 girls and 54 boys aged 1–5 years, who were enrolled in the 1-year programme “Learning to Eat from the Mediterranean”, designed to promote the adoption of a traditional Mediterranean diet. We studied the clinical and therapeutic variables and anthropometric measurements.


All studied symptomatic indicators (number and intensity of asthmatic attack, infections and hospital admissions) showed a positive and statistically significant evolution of bronchial hyperreactivity from the first weeks of the intervention onwards. Throughout the treatment, 32.2% of patients remained free of crisis, 35.3% of the patients only had one attack throughout the year and 24.9% had two episodes, compared to 4.73 episodes on average in the previous year. The use of inhaled corticosteroids markedly decreased from 3.92±1.61 to 1.11±1.09 times per patient per year (P<0.001) and that of inhaled bronchodilators decreased from 4.14±1.61 to 1.12±1.40 (P<0.001). As a result, the families involved in the programme reported a high level of satisfaction.


The adoption of a traditional Mediterranean diet could contribute significantly to the improvement of patients diagnosed with childhood asthma.

Bronchial hyperreactivity
Childhood asthma
Dietary pattern
Dietary programme
Mediterranean diet
Nutritional assessment


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